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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CYP4Z1
All Species:
3.64
Human Site:
S240
Identified Species:
8.89
UniProt:
Q86W10
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86W10
NP_835235.1
505
59086
S240
N
D
L
V
F
K
F
S
S
Q
G
Q
I
F
S
Chimpanzee
Pan troglodytes
XP_001141506
510
58133
S247
D
T
I
Y
S
L
T
S
A
G
R
W
T
H
R
Rhesus Macaque
Macaca mulatta
XP_001109135
519
59279
S247
D
T
I
Y
S
L
T
S
T
G
R
W
T
H
R
Dog
Lupus familis
XP_539622
507
58744
P242
D
I
I
F
K
F
S
P
Q
G
H
R
L
Q
E
Cat
Felis silvestris
Mouse
Mus musculus
O88833
509
58321
S246
D
T
I
Y
K
L
S
S
N
G
R
L
A
K
Q
Rat
Rattus norvegicus
Q8K4D6
507
58555
L240
H
H
D
I
I
F
K
L
S
P
K
G
H
C
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520882
506
58357
P241
N
F
I
Y
W
L
S
P
L
G
R
C
F
R
Q
Chicken
Gallus gallus
XP_422455
504
57538
H239
D
A
F
Y
D
L
T
H
S
S
R
E
F
Q
D
Frog
Xenopus laevis
NP_001091126
516
59853
P243
D
V
I
F
Y
L
S
P
L
G
F
R
F
R
R
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q27589
501
57896
D237
P
T
E
A
K
R
Q
D
K
A
I
K
V
M
H
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
55.4
50.8
55.6
N.A.
48.5
53.4
N.A.
49.5
49.1
50.7
N.A.
N.A.
32.2
N.A.
N.A.
N.A.
Protein Similarity:
100
71.9
68.2
73.1
N.A.
70.1
74.3
N.A.
70.3
67.5
66.8
N.A.
N.A.
52.8
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
6.6
0
N.A.
6.6
6.6
N.A.
6.6
6.6
0
N.A.
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
26.6
26.6
26.6
N.A.
26.6
20
N.A.
20
20
26.6
N.A.
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
10
0
0
0
0
10
10
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
10
0
10
0
% C
% Asp:
60
10
10
0
10
0
0
10
0
0
0
0
0
0
10
% D
% Glu:
0
0
10
0
0
0
0
0
0
0
0
10
0
0
10
% E
% Phe:
0
10
10
20
10
20
10
0
0
0
10
0
30
10
10
% F
% Gly:
0
0
0
0
0
0
0
0
0
60
10
10
0
0
0
% G
% His:
10
10
0
0
0
0
0
10
0
0
10
0
10
20
10
% H
% Ile:
0
10
60
10
10
0
0
0
0
0
10
0
10
0
0
% I
% Lys:
0
0
0
0
30
10
10
0
10
0
10
10
0
10
0
% K
% Leu:
0
0
10
0
0
60
0
10
20
0
0
10
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
20
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% N
% Pro:
10
0
0
0
0
0
0
30
0
10
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
10
0
10
10
0
10
0
20
20
% Q
% Arg:
0
0
0
0
0
10
0
0
0
0
50
20
0
20
30
% R
% Ser:
0
0
0
0
20
0
40
40
30
10
0
0
0
0
10
% S
% Thr:
0
40
0
0
0
0
30
0
10
0
0
0
20
0
0
% T
% Val:
0
10
0
10
0
0
0
0
0
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
10
0
0
0
0
0
0
20
0
0
0
% W
% Tyr:
0
0
0
50
10
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _