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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CYP4Z1
All Species:
6.97
Human Site:
S219
Identified Species:
17.04
UniProt:
Q86W10
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86W10
NP_835235.1
505
59086
S219
L
K
A
V
F
N
L
S
K
I
S
N
Q
R
M
Chimpanzee
Pan troglodytes
XP_001141506
510
58133
N225
I
Q
A
I
S
D
L
N
N
L
V
F
S
R
V
Rhesus Macaque
Macaca mulatta
XP_001109135
519
59279
N225
I
Q
A
I
S
D
L
N
N
L
T
F
S
R
A
Dog
Lupus familis
XP_539622
507
58744
S220
V
K
T
T
F
E
A
S
K
I
N
F
Y
R
L
Cat
Felis silvestris
Mouse
Mus musculus
O88833
509
58321
N224
L
Q
A
I
G
D
L
N
N
L
F
H
S
R
V
Rat
Rattus norvegicus
Q8K4D6
507
58555
G220
V
K
A
T
F
E
L
G
E
I
I
S
S
R
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520882
506
58357
T219
I
Q
A
V
N
N
L
T
S
M
I
S
Q
R
I
Chicken
Gallus gallus
XP_422455
504
57538
I221
V
F
D
L
G
Y
L
I
N
K
R
I
Q
N
F
Frog
Xenopus laevis
NP_001091126
516
59853
Y222
K
A
V
Y
E
L
S
Y
L
L
D
Q
R
S
R
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q27589
501
57896
N208
Q
A
V
N
D
V
T
N
I
L
I
K
R
F
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
55.4
50.8
55.6
N.A.
48.5
53.4
N.A.
49.5
49.1
50.7
N.A.
N.A.
32.2
N.A.
N.A.
N.A.
Protein Similarity:
100
71.9
68.2
73.1
N.A.
70.1
74.3
N.A.
70.3
67.5
66.8
N.A.
N.A.
52.8
N.A.
N.A.
N.A.
P-Site Identity:
100
20
20
40
N.A.
26.6
40
N.A.
40
13.3
0
N.A.
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
66.6
66.6
60
N.A.
73.3
66.6
N.A.
80
26.6
13.3
N.A.
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
20
60
0
0
0
10
0
0
0
0
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
10
30
0
0
0
0
10
0
0
0
0
% D
% Glu:
0
0
0
0
10
20
0
0
10
0
0
0
0
0
0
% E
% Phe:
0
10
0
0
30
0
0
0
0
0
10
30
0
10
10
% F
% Gly:
0
0
0
0
20
0
0
10
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% H
% Ile:
30
0
0
30
0
0
0
10
10
30
30
10
0
0
20
% I
% Lys:
10
30
0
0
0
0
0
0
20
10
0
10
0
0
0
% K
% Leu:
20
0
0
10
0
10
70
0
10
50
0
0
0
0
20
% L
% Met:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
10
% M
% Asn:
0
0
0
10
10
20
0
40
40
0
10
10
0
10
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
10
40
0
0
0
0
0
0
0
0
0
10
30
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
10
0
20
70
10
% R
% Ser:
0
0
0
0
20
0
10
20
10
0
10
20
40
10
0
% S
% Thr:
0
0
10
20
0
0
10
10
0
0
10
0
0
0
0
% T
% Val:
30
0
20
20
0
10
0
0
0
0
10
0
0
0
20
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
10
0
10
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _