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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TXNRD3
All Species:
8.48
Human Site:
S85
Identified Species:
13.33
UniProt:
Q86VQ6
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86VQ6
NP_001087240
682
74823
S85
R
L
S
S
P
G
P
S
R
S
S
E
A
R
E
Chimpanzee
Pan troglodytes
XP_516719
752
82205
S157
R
L
S
S
P
G
P
S
R
S
S
E
A
R
E
Rhesus Macaque
Macaca mulatta
NP_001152971
524
56314
Dog
Lupus familis
XP_850181
509
55065
Cat
Felis silvestris
Mouse
Mus musculus
Q99MD6
697
75946
S99
R
L
A
S
P
G
T
S
R
P
S
S
E
A
R
Rat
Rattus norvegicus
O89049
498
54218
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507796
621
68478
S78
L
S
N
N
I
E
S
S
E
D
T
S
N
A
N
Chicken
Gallus gallus
NP_001116249
606
66439
G64
E
L
D
V
T
D
D
G
P
S
I
Q
Q
V
L
Frog
Xenopus laevis
NP_001087660
596
65709
E54
Y
H
S
L
E
L
D
E
C
D
D
G
S
D
I
Zebra Danio
Brachydanio rerio
NP_898895
602
65949
E60
T
I
E
L
D
L
M
E
D
G
T
N
Y
Q
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91938
596
64304
Q54
S
C
A
H
H
T
F
Q
R
T
M
N
L
T
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q17745
667
74094
D88
V
I
F
Y
N
S
S
D
E
E
K
Q
L
V
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P42770
565
60834
K23
P
S
L
Q
F
L
C
K
K
L
P
I
A
I
H
Baker's Yeast
Sacchar. cerevisiae
P41921
483
53422
Red Bread Mold
Neurospora crassa
Q873E8
468
50294
Conservation
Percent
Protein Identity:
100
89.7
43.5
42.6
N.A.
82.3
54.6
N.A.
58
68
65
63.9
N.A.
44.1
N.A.
46.9
N.A.
Protein Similarity:
100
90
54.6
53.6
N.A.
90.5
63.3
N.A.
71.9
79
78.1
76.2
N.A.
57.3
N.A.
63.7
N.A.
P-Site Identity:
100
100
0
0
N.A.
53.3
0
N.A.
6.6
13.3
6.6
0
N.A.
6.6
N.A.
6.6
N.A.
P-Site Similarity:
100
100
0
0
N.A.
60
0
N.A.
26.6
20
13.3
26.6
N.A.
20
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.2
24.3
25.6
Protein Similarity:
N.A.
N.A.
N.A.
46.9
42.8
40.9
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
0
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
0
0
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
14
0
0
0
0
0
0
0
0
0
20
14
0
% A
% Cys:
0
7
0
0
0
0
7
0
7
0
0
0
0
0
0
% C
% Asp:
0
0
7
0
7
7
14
7
7
14
7
0
0
7
7
% D
% Glu:
7
0
7
0
7
7
0
14
14
7
0
14
7
0
20
% E
% Phe:
0
0
7
0
7
0
7
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
20
0
7
0
7
0
7
0
0
7
% G
% His:
0
7
0
7
7
0
0
0
0
0
0
0
0
0
7
% H
% Ile:
0
14
0
0
7
0
0
0
0
0
7
7
0
7
7
% I
% Lys:
0
0
0
0
0
0
0
7
7
0
7
0
0
0
0
% K
% Leu:
7
27
7
14
0
20
0
0
0
7
0
0
14
0
7
% L
% Met:
0
0
0
0
0
0
7
0
0
0
7
0
0
0
0
% M
% Asn:
0
0
7
7
7
0
0
0
0
0
0
14
7
0
7
% N
% Pro:
7
0
0
0
20
0
14
0
7
7
7
0
0
0
0
% P
% Gln:
0
0
0
7
0
0
0
7
0
0
0
14
7
7
0
% Q
% Arg:
20
0
0
0
0
0
0
0
27
0
0
0
0
14
7
% R
% Ser:
7
14
20
20
0
7
14
27
0
20
20
14
7
0
0
% S
% Thr:
7
0
0
0
7
7
7
0
0
7
14
0
0
7
0
% T
% Val:
7
0
0
7
0
0
0
0
0
0
0
0
0
14
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
7
0
0
0
0
0
0
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _