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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CAND1
All Species:
44.55
Human Site:
Y772
Identified Species:
81.67
UniProt:
Q86VP6
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86VP6
NP_060918.2
1230
136376
Y772
T
G
T
N
N
L
G
Y
M
D
L
L
R
M
L
Chimpanzee
Pan troglodytes
XP_509204
1350
150071
Y892
T
G
T
N
N
L
G
Y
M
D
L
L
R
M
L
Rhesus Macaque
Macaca mulatta
XP_001106780
1351
150139
Y893
T
G
T
N
N
L
G
Y
M
D
L
L
R
M
L
Dog
Lupus familis
XP_531667
1206
133582
Y748
T
G
T
N
N
L
G
Y
M
D
L
L
R
M
L
Cat
Felis silvestris
Mouse
Mus musculus
Q6ZQ38
1230
136313
Y772
T
G
T
N
N
L
G
Y
M
D
L
L
R
M
L
Rat
Rattus norvegicus
P97536
1230
136343
Y772
T
G
T
N
N
L
G
Y
M
D
L
L
R
M
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511066
1243
137773
Y785
T
G
T
S
N
L
G
Y
M
D
L
L
R
M
L
Chicken
Gallus gallus
XP_416078
1191
131738
Y733
T
G
T
N
N
L
G
Y
M
D
L
L
R
M
L
Frog
Xenopus laevis
NP_001085373
1230
136368
Y772
T
G
T
A
T
L
G
Y
M
D
L
L
R
M
L
Zebra Danio
Brachydanio rerio
NP_998650
1230
136018
Y772
T
G
T
A
S
L
G
Y
M
D
L
L
R
M
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609389
1248
139337
Y771
T
Q
L
S
G
L
D
Y
H
S
L
V
S
K
L
Honey Bee
Apis mellifera
XP_393409
1235
138752
Y773
A
D
I
P
G
L
G
Y
R
E
L
L
S
M
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791290
981
108569
E551
V
K
V
I
R
P
L
E
K
D
N
G
F
D
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91
91
97.9
N.A.
99.4
99.7
N.A.
96.4
94.2
97.1
93.8
N.A.
58.8
68
N.A.
57.8
Protein Similarity:
100
91.1
91
98
N.A.
99.7
99.8
N.A.
97.7
95.8
98.5
97
N.A.
75.8
82.4
N.A.
69.1
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
93.3
100
86.6
86.6
N.A.
33.3
46.6
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
86.6
93.3
N.A.
46.6
53.3
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
16
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
0
8
0
0
85
0
0
0
8
0
% D
% Glu:
0
0
0
0
0
0
0
8
0
8
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
8
% F
% Gly:
0
77
0
0
16
0
85
0
0
0
0
8
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
0
0
8
8
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
8
0
0
0
0
0
0
8
0
0
0
0
8
0
% K
% Leu:
0
0
8
0
0
93
8
0
0
0
93
85
0
0
93
% L
% Met:
0
0
0
0
0
0
0
0
77
0
0
0
0
85
0
% M
% Asn:
0
0
0
54
62
0
0
0
0
0
8
0
0
0
0
% N
% Pro:
0
0
0
8
0
8
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
8
0
0
0
8
0
0
0
77
0
0
% R
% Ser:
0
0
0
16
8
0
0
0
0
8
0
0
16
0
0
% S
% Thr:
85
0
77
0
8
0
0
0
0
0
0
0
0
0
0
% T
% Val:
8
0
8
0
0
0
0
0
0
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
93
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _