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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS36
All Species:
47.27
Human Site:
Y378
Identified Species:
74.29
UniProt:
Q86VN1
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86VN1
NP_057159.2
386
43817
Y378
S
V
E
G
L
R
F
Y
P
N
L
F
M
T
Q
Chimpanzee
Pan troglodytes
XP_001134797
377
42708
Y369
S
V
E
G
L
R
F
Y
P
N
L
F
M
T
Q
Rhesus Macaque
Macaca mulatta
XP_001082759
386
43783
Y378
S
V
E
G
L
R
F
Y
P
N
L
F
M
T
Q
Dog
Lupus familis
XP_534484
386
43758
Y378
S
V
E
G
L
R
F
Y
P
N
L
F
M
T
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q91XD6
386
43717
Y378
S
V
E
G
L
R
F
Y
P
N
L
F
M
T
Q
Rat
Rattus norvegicus
P0C0A2
386
43699
Y378
S
V
E
G
L
R
F
Y
P
N
L
F
M
T
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513182
358
40422
Y350
S
V
E
G
L
R
F
Y
P
N
L
F
M
T
Q
Chicken
Gallus gallus
XP_417077
386
43557
Y378
S
V
E
G
L
R
F
Y
P
N
L
F
L
T
Q
Frog
Xenopus laevis
Q6DDF4
388
43900
Y380
S
V
E
G
L
R
F
Y
P
N
L
F
L
T
Q
Zebra Danio
Brachydanio rerio
Q7ZVK4
382
43262
L375
R
D
D
S
V
E
G
L
R
F
Y
P
N
L
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VU87
399
44195
Y391
S
V
E
G
L
R
F
Y
P
N
L
L
L
G
R
Honey Bee
Apis mellifera
XP_395542
402
45958
Y393
T
I
E
A
L
R
F
Y
P
N
L
F
L
E
K
Nematode Worm
Caenorhab. elegans
NP_505798
383
42691
F376
D
S
I
E
G
L
L
F
Y
P
N
R
F
M
E
Sea Urchin
Strong. purpuratus
XP_796608
328
36233
L321
G
L
R
F
F
P
N
L
F
L
N
P
P
S
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FF81
440
49015
Y407
S
P
D
G
L
R
F
Y
F
N
L
F
P
E
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.6
99.4
98.9
N.A.
95.8
95.8
N.A.
86.7
89.6
86
84.1
N.A.
46.6
48.7
41.9
51.3
Protein Similarity:
100
97.6
100
99.2
N.A.
98.9
98.6
N.A.
89.9
95
92.7
92.7
N.A.
66.9
69.6
64.7
66.5
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
93.3
93.3
0
N.A.
73.3
60
0
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
100
13.3
N.A.
86.6
86.6
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
34.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
51.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
60
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
7
14
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
74
7
0
7
0
0
0
0
0
0
0
14
7
% E
% Phe:
0
0
0
7
7
0
80
7
14
7
0
74
7
0
7
% F
% Gly:
7
0
0
74
7
0
7
0
0
0
0
0
0
7
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
7
7
0
0
0
0
0
0
0
0
0
0
0
7
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% K
% Leu:
0
7
0
0
80
7
7
14
0
7
80
7
27
7
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
47
7
0
% M
% Asn:
0
0
0
0
0
0
7
0
0
80
14
0
7
0
0
% N
% Pro:
0
7
0
0
0
7
0
0
74
7
0
14
14
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
60
% Q
% Arg:
7
0
7
0
0
80
0
0
7
0
0
7
0
0
14
% R
% Ser:
74
7
0
7
0
0
0
0
0
0
0
0
0
7
0
% S
% Thr:
7
0
0
0
0
0
0
0
0
0
0
0
0
60
0
% T
% Val:
0
67
0
0
7
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
80
7
0
7
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _