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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PIGZ All Species: 5.76
Human Site: S89 Identified Species: 11.52
UniProt: Q86VD9 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86VD9 NP_079439.2 579 63473 S89 W E F Y P S S S C R S V L F P
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001096610 446 48480 V10 G P T C K E P V P G P W W H S
Dog Lupus familis XP_545157 592 64399 S89 W E F Q A A S S C R S P L L P
Cat Felis silvestris
Mouse Mus musculus Q8BTP0 560 62025 S73 F P L L T S G S T F W L L R L
Rat Rattus norvegicus XP_002724776 558 61646 W79 T F W L L R L W E E L G L W P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512679 710 75710 P208 W E F Q A G S P C R T A V F P
Chicken Gallus gallus XP_426699 559 62255 K77 G V A Y W V L K A L Q Q L D V
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q7SXZ1 536 62222 E92 Y E T W E W K E G I R G Y S Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8MT80 696 80199 R73 F N N S L P V R S I V L P F A
Honey Bee Apis mellifera XP_624036 592 68391 P78 W E F N S T F P I R T V L I S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001204359 586 65351 A81 F H L L R K L A E L G L V A V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q04174 516 59882 T73 L V Y G P L F T I L E S F P E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 61.3 77.8 N.A. 75.9 75.6 N.A. 51.9 48.8 N.A. 21.4 N.A. 26.8 25.5 N.A. 28.5
Protein Similarity: 100 N.A. 62.5 82.9 N.A. 82.2 82.3 N.A. 59.2 62.3 N.A. 34.3 N.A. 39.6 44.5 N.A. 47.2
P-Site Identity: 100 N.A. 0 66.6 N.A. 20 13.3 N.A. 53.3 13.3 N.A. 6.6 N.A. 6.6 40 N.A. 0
P-Site Similarity: 100 N.A. 0 73.3 N.A. 33.3 26.6 N.A. 66.6 13.3 N.A. 20 N.A. 20 53.3 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 23.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 39.2 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 9 0 17 9 0 9 9 0 0 9 0 9 9 % A
% Cys: 0 0 0 9 0 0 0 0 25 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % D
% Glu: 0 42 0 0 9 9 0 9 17 9 9 0 0 0 9 % E
% Phe: 25 9 34 0 0 0 17 0 0 9 0 0 9 25 0 % F
% Gly: 17 0 0 9 0 9 9 0 9 9 9 17 0 0 0 % G
% His: 0 9 0 0 0 0 0 0 0 0 0 0 0 9 0 % H
% Ile: 0 0 0 0 0 0 0 0 17 17 0 0 0 9 0 % I
% Lys: 0 0 0 0 9 9 9 9 0 0 0 0 0 0 0 % K
% Leu: 9 0 17 25 17 9 25 0 0 25 9 25 50 9 9 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 9 9 9 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 17 0 0 17 9 9 17 9 0 9 9 9 9 34 % P
% Gln: 0 0 0 17 0 0 0 0 0 0 9 9 0 0 0 % Q
% Arg: 0 0 0 0 9 9 0 9 0 34 9 0 0 9 0 % R
% Ser: 0 0 0 9 9 17 25 25 9 0 17 9 0 9 17 % S
% Thr: 9 0 17 0 9 9 0 9 9 0 17 0 0 0 0 % T
% Val: 0 17 0 0 0 9 9 9 0 0 9 17 17 0 17 % V
% Trp: 34 0 9 9 9 9 0 9 0 0 9 9 9 9 0 % W
% Tyr: 9 0 9 17 0 0 0 0 0 0 0 0 9 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _