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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
THOC4
All Species:
12.42
Human Site:
S18
Identified Species:
30.37
UniProt:
Q86V81
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86V81
NP_005773
257
26888
S18
D
I
I
K
L
N
R
S
Q
R
G
G
R
G
G
Chimpanzee
Pan troglodytes
XP_001165277
257
27139
S18
D
I
I
K
L
N
R
S
Q
R
G
G
R
G
G
Rhesus Macaque
Macaca mulatta
XP_001112225
257
26872
S18
D
I
I
K
L
N
R
S
Q
R
G
G
R
G
G
Dog
Lupus familis
XP_849911
187
19920
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJW6
218
23712
K14
M
S
L
D
D
I
I
K
L
N
R
N
Q
R
R
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q58EA2
256
26996
S18
D
I
I
K
L
N
R
S
Q
R
P
S
G
R
G
Zebra Danio
Brachydanio rerio
NP_001098578
280
28579
Q18
D
I
I
K
Q
N
R
Q
R
G
G
G
G
G
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P48810
385
39481
L23
E
I
T
E
P
E
Q
L
R
K
L
F
I
G
G
Honey Bee
Apis mellifera
XP_001121250
247
26707
G18
D
I
I
K
Q
N
K
G
S
R
P
R
G
G
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782040
304
30423
G19
D
I
I
K
T
N
R
G
N
R
G
G
R
G
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.6
99.2
68.8
N.A.
75.8
N.A.
N.A.
N.A.
N.A.
80.9
73.9
N.A.
20.5
52.5
N.A.
55.5
Protein Similarity:
100
97.6
99.6
70.4
N.A.
79.3
N.A.
N.A.
N.A.
N.A.
82.8
77.1
N.A.
29
63
N.A.
64.1
P-Site Identity:
100
100
100
0
N.A.
0
N.A.
N.A.
N.A.
N.A.
73.3
60
N.A.
20
46.6
N.A.
80
P-Site Similarity:
100
100
100
0
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
73.3
66.6
N.A.
53.3
53.3
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
70
0
0
10
10
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
10
0
0
10
0
10
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
20
0
10
50
50
30
70
60
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
80
70
0
0
10
10
0
0
0
0
0
10
0
0
% I
% Lys:
0
0
0
70
0
0
10
10
0
10
0
0
0
0
0
% K
% Leu:
0
0
10
0
40
0
0
10
10
0
10
0
0
0
0
% L
% Met:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
70
0
0
10
10
0
10
0
0
0
% N
% Pro:
0
0
0
0
10
0
0
0
0
0
20
0
0
0
0
% P
% Gln:
0
0
0
0
20
0
10
10
40
0
0
0
10
0
0
% Q
% Arg:
0
0
0
0
0
0
60
0
20
60
10
10
40
20
20
% R
% Ser:
0
10
0
0
0
0
0
40
10
0
0
10
0
0
0
% S
% Thr:
0
0
10
0
10
0
0
0
0
0
0
0
0
0
10
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _