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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM83A
All Species:
30
Human Site:
Y290
Identified Species:
73.33
UniProt:
Q86UY5
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86UY5
NP_116288.2
434
47458
Y290
D
E
E
F
R
H
L
Y
A
S
S
K
P
V
M
Chimpanzee
Pan troglodytes
XP_001147027
434
47418
Y290
D
E
E
F
R
H
L
Y
A
S
S
K
P
V
M
Rhesus Macaque
Macaca mulatta
XP_001099761
434
47657
Y290
D
E
E
F
R
H
L
Y
A
S
S
K
P
V
M
Dog
Lupus familis
XP_851601
392
42797
L261
M
G
P
K
S
P
R
L
G
A
P
L
Q
P
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8K2P2
436
48174
Y290
D
E
E
F
R
R
L
Y
A
S
S
K
P
L
M
Rat
Rattus norvegicus
NP_001124048
436
48260
Y290
D
E
E
F
R
R
L
Y
A
S
S
K
P
L
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506192
427
47555
Y286
D
E
E
F
R
H
L
Y
A
I
S
K
P
V
V
Chicken
Gallus gallus
XP_001233861
470
53107
Y321
D
E
E
F
R
H
L
Y
A
L
S
K
P
V
R
Frog
Xenopus laevis
Q6PF42
443
50454
Y288
D
E
E
F
R
H
L
Y
G
S
S
K
P
V
M
Zebra Danio
Brachydanio rerio
XP_001340276
405
46003
K264
R
S
L
A
V
L
F
K
G
S
G
V
K
P
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
96
71.1
N.A.
81.8
80.9
N.A.
55.5
51.7
51.6
37
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.3
96.7
77.1
N.A.
87.1
86.6
N.A.
65.6
63.4
66.3
52.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
0
N.A.
86.6
86.6
N.A.
86.6
86.6
93.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
6.6
N.A.
93.3
93.3
N.A.
93.3
86.6
93.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
0
0
70
10
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
80
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
80
80
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
80
0
0
10
0
0
0
0
0
0
0
10
% F
% Gly:
0
10
0
0
0
0
0
0
30
0
10
0
0
0
0
% G
% His:
0
0
0
0
0
60
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% I
% Lys:
0
0
0
10
0
0
0
10
0
0
0
80
10
0
0
% K
% Leu:
0
0
10
0
0
10
80
10
0
10
0
10
0
20
0
% L
% Met:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
60
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
10
0
0
10
0
0
0
0
10
0
80
20
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% Q
% Arg:
10
0
0
0
80
20
10
0
0
0
0
0
0
0
20
% R
% Ser:
0
10
0
0
10
0
0
0
0
70
80
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
10
0
0
0
0
0
0
10
0
60
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
80
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _