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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZNF598 All Species: 27.27
Human Site: Y224 Identified Species: 50
UniProt: Q86UK7 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86UK7 NP_835461.1 904 98637 Y224 D S D G A Q D Y Y S D Y A Y L
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001082834 548 62617
Dog Lupus familis XP_547181 909 98805 Y224 D S D G A Q D Y Y S D Y A Y L
Cat Felis silvestris
Mouse Mus musculus Q80YR4 908 99174 Y222 D S D G A Q D Y Y S D Y A Y L
Rat Rattus norvegicus NP_001099240 902 98835 Y221 D A D G A Q D Y Y S D Y A Y L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001233824 883 98619 Y216 D S D G A Q E Y Y S D Y E Y L
Frog Xenopus laevis NP_001089231 889 99603 Y189 D S E G A Q E Y Y S D Y T F L
Zebra Danio Brachydanio rerio Q6PFK1 953 106893 Y252 D A D G A Q E Y Y S D Y Q Y L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611932 867 95920 D220 N K R Y V D R D E L F R H L R
Honey Bee Apis mellifera XP_391897 814 92277 M173 E F C D Q R Y M D N D E L F R
Nematode Worm Caenorhab. elegans NP_495439 925 102667 C215 S R H E Q S Y C H I C T D N L
Sea Urchin Strong. purpuratus XP_788063 833 93080 H189 D N D E L H R H L R K D H Y F
Poplar Tree Populus trichocarpa XP_002302796 819 91004 S178 Q H I S T G D S D V D G S E S
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 59.4 82.7 N.A. 81.9 81.6 N.A. N.A. 61.6 54.3 49.5 N.A. 31.4 30.7 20.4 33
Protein Similarity: 100 N.A. 59.8 87.9 N.A. 86.8 86.7 N.A. N.A. 73.8 65.3 63.5 N.A. 46.9 45.3 36.4 49.4
P-Site Identity: 100 N.A. 0 100 N.A. 100 93.3 N.A. N.A. 86.6 73.3 80 N.A. 0 6.6 6.6 20
P-Site Similarity: 100 N.A. 0 100 N.A. 100 100 N.A. N.A. 93.3 93.3 93.3 N.A. 6.6 33.3 13.3 33.3
Percent
Protein Identity: 20.3 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 35.7 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 20 N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 16 0 0 54 0 0 0 0 0 0 0 31 0 0 % A
% Cys: 0 0 8 0 0 0 0 8 0 0 8 0 0 0 0 % C
% Asp: 62 0 54 8 0 8 39 8 16 0 70 8 8 0 0 % D
% Glu: 8 0 8 16 0 0 24 0 8 0 0 8 8 8 0 % E
% Phe: 0 8 0 0 0 0 0 0 0 0 8 0 0 16 8 % F
% Gly: 0 0 0 54 0 8 0 0 0 0 0 8 0 0 0 % G
% His: 0 8 8 0 0 8 0 8 8 0 0 0 16 0 0 % H
% Ile: 0 0 8 0 0 0 0 0 0 8 0 0 0 0 0 % I
% Lys: 0 8 0 0 0 0 0 0 0 0 8 0 0 0 0 % K
% Leu: 0 0 0 0 8 0 0 0 8 8 0 0 8 8 62 % L
% Met: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % M
% Asn: 8 8 0 0 0 0 0 0 0 8 0 0 0 8 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 8 0 0 0 16 54 0 0 0 0 0 0 8 0 0 % Q
% Arg: 0 8 8 0 0 8 16 0 0 8 0 8 0 0 16 % R
% Ser: 8 39 0 8 0 8 0 8 0 54 0 0 8 0 8 % S
% Thr: 0 0 0 0 8 0 0 0 0 0 0 8 8 0 0 % T
% Val: 0 0 0 0 8 0 0 0 0 8 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 8 0 0 16 54 54 0 0 54 0 54 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _