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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZNF598
All Species:
7.88
Human Site:
T600
Identified Species:
14.44
UniProt:
Q86UK7
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86UK7
NP_835461.1
904
98637
T600
V
G
S
E
K
P
G
T
T
L
P
Q
P
P
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001082834
548
62617
L262
A
F
R
T
E
I
D
L
K
A
H
R
T
A
C
Dog
Lupus familis
XP_547181
909
98805
S607
S
E
K
P
G
A
T
S
P
P
L
P
L
P
D
Cat
Felis silvestris
Mouse
Mus musculus
Q80YR4
908
99174
S598
E
K
P
G
A
T
S
S
P
L
L
P
P
D
H
Rat
Rattus norvegicus
NP_001099240
902
98835
S592
E
K
P
G
A
T
S
S
P
L
L
P
P
D
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001233824
883
98619
T590
S
P
H
L
L
Q
E
T
S
L
P
R
S
C
I
Frog
Xenopus laevis
NP_001089231
889
99603
Q581
V
G
S
E
K
Q
H
Q
S
S
A
T
Q
P
V
Zebra Danio
Brachydanio rerio
Q6PFK1
953
106893
S639
K
K
K
Q
T
T
A
S
S
L
G
S
P
S
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611932
867
95920
S577
T
T
A
P
K
P
S
S
G
S
P
S
L
N
W
Honey Bee
Apis mellifera
XP_391897
814
92277
N528
G
Q
P
Q
N
S
N
N
I
K
K
E
C
E
T
Nematode Worm
Caenorhab. elegans
NP_495439
925
102667
S600
A
N
S
S
W
L
N
S
K
N
S
K
I
K
S
Sea Urchin
Strong. purpuratus
XP_788063
833
93080
P545
A
Q
S
A
S
Q
D
P
K
V
M
N
Y
R
S
Poplar Tree
Populus trichocarpa
XP_002302796
819
91004
K533
L
A
D
S
G
S
L
K
P
S
V
S
D
F
P
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
59.4
82.7
N.A.
81.9
81.6
N.A.
N.A.
61.6
54.3
49.5
N.A.
31.4
30.7
20.4
33
Protein Similarity:
100
N.A.
59.8
87.9
N.A.
86.8
86.7
N.A.
N.A.
73.8
65.3
63.5
N.A.
46.9
45.3
36.4
49.4
P-Site Identity:
100
N.A.
0
6.6
N.A.
13.3
13.3
N.A.
N.A.
20
40
13.3
N.A.
20
0
6.6
6.6
P-Site Similarity:
100
N.A.
13.3
13.3
N.A.
20
20
N.A.
N.A.
33.3
46.6
33.3
N.A.
33.3
13.3
20
13.3
Percent
Protein Identity:
20.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
35.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
24
8
8
8
16
8
8
0
0
8
8
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
8
8
% C
% Asp:
0
0
8
0
0
0
16
0
0
0
0
0
8
16
8
% D
% Glu:
16
8
0
16
8
0
8
0
0
0
0
8
0
8
0
% E
% Phe:
0
8
0
0
0
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
8
16
0
16
16
0
8
0
8
0
8
0
0
0
0
% G
% His:
0
0
8
0
0
0
8
0
0
0
8
0
0
0
24
% H
% Ile:
0
0
0
0
0
8
0
0
8
0
0
0
8
0
8
% I
% Lys:
8
24
16
0
24
0
0
8
24
8
8
8
0
8
0
% K
% Leu:
8
0
0
8
8
8
8
8
0
39
24
0
16
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
8
0
0
8
0
16
8
0
8
0
8
0
8
0
% N
% Pro:
0
8
24
16
0
16
0
8
31
8
24
24
31
24
16
% P
% Gln:
0
16
0
16
0
24
0
8
0
0
0
8
8
0
0
% Q
% Arg:
0
0
8
0
0
0
0
0
0
0
0
16
0
8
0
% R
% Ser:
16
0
31
16
8
16
24
47
24
24
8
24
8
8
16
% S
% Thr:
8
8
0
8
8
24
8
16
8
0
0
8
8
0
8
% T
% Val:
16
0
0
0
0
0
0
0
0
8
8
0
0
0
8
% V
% Trp:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _