KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZNF598
All Species:
9.39
Human Site:
S776
Identified Species:
17.22
UniProt:
Q86UK7
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86UK7
NP_835461.1
904
98637
S776
Q
S
D
E
A
R
F
S
E
F
K
S
H
S
G
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001082834
548
62617
R429
A
T
P
C
L
T
L
R
R
Q
G
L
I
S
A
Dog
Lupus familis
XP_547181
909
98805
G781
Q
S
D
E
A
R
F
G
Q
F
K
S
H
S
G
Cat
Felis silvestris
Mouse
Mus musculus
Q80YR4
908
99174
S780
Q
S
D
E
A
C
F
S
K
F
K
S
H
S
G
Rat
Rattus norvegicus
NP_001099240
902
98835
S774
Q
S
D
E
A
C
F
S
K
F
K
S
H
S
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001233824
883
98619
N757
Q
S
D
E
S
K
F
N
K
F
K
T
H
S
G
Frog
Xenopus laevis
NP_001089231
889
99603
N762
D
S
D
E
S
K
F
N
E
F
K
S
L
S
G
Zebra Danio
Brachydanio rerio
Q6PFK1
953
106893
N822
Q
N
D
E
T
K
F
N
E
F
K
N
Y
S
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611932
867
95920
L745
L
V
D
E
V
M
S
L
L
K
T
P
E
A
L
Honey Bee
Apis mellifera
XP_391897
814
92277
I695
L
V
A
K
V
N
E
I
L
M
Q
H
D
D
Q
Nematode Worm
Caenorhab. elegans
NP_495439
925
102667
S781
S
Q
S
S
I
V
P
S
A
P
K
V
D
S
L
Sea Urchin
Strong. purpuratus
XP_788063
833
93080
F714
Q
T
L
S
E
E
N
F
Q
S
V
F
N
E
L
Poplar Tree
Populus trichocarpa
XP_002302796
819
91004
V700
L
Q
S
N
Y
K
P
V
E
D
E
A
Q
L
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
59.4
82.7
N.A.
81.9
81.6
N.A.
N.A.
61.6
54.3
49.5
N.A.
31.4
30.7
20.4
33
Protein Similarity:
100
N.A.
59.8
87.9
N.A.
86.8
86.7
N.A.
N.A.
73.8
65.3
63.5
N.A.
46.9
45.3
36.4
49.4
P-Site Identity:
100
N.A.
6.6
86.6
N.A.
86.6
86.6
N.A.
N.A.
66.6
66.6
60
N.A.
13.3
0
20
6.6
P-Site Similarity:
100
N.A.
13.3
93.3
N.A.
93.3
93.3
N.A.
N.A.
100
86.6
93.3
N.A.
20
13.3
20
26.6
Percent
Protein Identity:
20.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
35.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
31
0
0
0
8
0
0
8
0
8
8
% A
% Cys:
0
0
0
8
0
16
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
62
0
0
0
0
0
0
8
0
0
16
8
0
% D
% Glu:
0
0
0
62
8
8
8
0
31
0
8
0
8
8
0
% E
% Phe:
0
0
0
0
0
0
54
8
0
54
0
8
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
8
0
0
8
0
0
0
54
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
39
0
0
% H
% Ile:
0
0
0
0
8
0
0
8
0
0
0
0
8
0
0
% I
% Lys:
0
0
0
8
0
31
0
0
24
8
62
0
0
0
0
% K
% Leu:
24
0
8
0
8
0
8
8
16
0
0
8
8
8
31
% L
% Met:
0
0
0
0
0
8
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
8
0
8
0
8
8
24
0
0
0
8
8
0
0
% N
% Pro:
0
0
8
0
0
0
16
0
0
8
0
8
0
0
0
% P
% Gln:
54
16
0
0
0
0
0
0
16
8
8
0
8
0
8
% Q
% Arg:
0
0
0
0
0
16
0
8
8
0
0
0
0
0
0
% R
% Ser:
8
47
16
16
16
0
8
31
0
8
0
39
0
70
0
% S
% Thr:
0
16
0
0
8
8
0
0
0
0
8
8
0
0
0
% T
% Val:
0
16
0
0
16
8
0
8
0
0
8
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _