KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PBRM1
All Species:
26.67
Human Site:
T1677
Identified Species:
65.19
UniProt:
Q86U86
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86U86
NP_060635.2
1689
192948
T1677
R
D
L
M
L
R
D
T
L
N
I
R
Q
A
Y
Chimpanzee
Pan troglodytes
XP_516515
1648
188792
T1636
R
D
L
M
L
R
D
T
L
N
I
R
Q
A
Y
Rhesus Macaque
Macaca mulatta
XP_001087934
1689
192798
T1677
R
D
L
M
L
R
D
T
L
N
I
R
Q
A
Y
Dog
Lupus familis
XP_849549
1689
192968
T1677
R
D
L
M
L
R
D
T
L
N
I
R
Q
A
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q8BSQ9
1634
187200
T1622
R
D
L
M
L
R
D
T
L
N
I
R
Q
A
Y
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90941
1633
187037
T1621
R
D
L
M
L
R
D
T
L
N
I
R
Q
A
Y
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_693735
1581
182705
T1569
R
D
L
M
L
R
D
T
L
N
I
Q
H
T
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_625055
1673
191341
M1661
A
L
W
T
L
R
N
M
M
M
R
D
V
L
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796375
1817
207298
F1772
R
D
I
M
Q
N
D
F
L
Q
V
S
R
A
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q06488
889
102281
R878
S
A
K
F
T
A
H
R
L
S
M
L
R
P
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.6
98.8
98.8
N.A.
94.8
N.A.
N.A.
N.A.
87.9
N.A.
71.1
N.A.
N.A.
38.1
N.A.
40.6
Protein Similarity:
100
96.6
99.2
99.5
N.A.
95.9
N.A.
N.A.
N.A.
92.8
N.A.
82.2
N.A.
N.A.
59.2
N.A.
59.1
P-Site Identity:
100
100
100
100
N.A.
100
N.A.
N.A.
N.A.
100
N.A.
80
N.A.
N.A.
13.3
N.A.
40
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
N.A.
100
N.A.
86.6
N.A.
N.A.
26.6
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
32
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
0
0
10
0
0
0
0
0
0
0
70
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
80
0
0
0
0
80
0
0
0
0
10
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
10
0
0
0
10
0
0
0
0
0
0
10
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
10
0
0
0
0
0
10
0
0
% H
% Ile:
0
0
10
0
0
0
0
0
0
0
70
0
0
0
0
% I
% Lys:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
10
70
0
80
0
0
0
90
0
0
10
0
10
0
% L
% Met:
0
0
0
80
0
0
0
10
10
10
10
0
0
0
0
% M
% Asn:
0
0
0
0
0
10
10
0
0
70
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
10
% P
% Gln:
0
0
0
0
10
0
0
0
0
10
0
10
60
0
0
% Q
% Arg:
80
0
0
0
0
80
0
10
0
0
10
60
20
0
0
% R
% Ser:
10
0
0
0
0
0
0
0
0
10
0
10
0
0
0
% S
% Thr:
0
0
0
10
10
0
0
70
0
0
0
0
0
10
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
10
0
10
0
0
% V
% Trp:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
70
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _