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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PABPN1 All Species: 27.58
Human Site: S235 Identified Species: 50.56
UniProt: Q86U42 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86U42 NP_004634.1 306 32749 S235 T S L A L D E S L F R G R Q I
Chimpanzee Pan troglodytes XP_509852 296 31478 S221 G F A Y I E F S D K E S V R T
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_858764 333 37180 S262 T S L A L D E S L F R G R Q I
Cat Felis silvestris
Mouse Mus musculus Q8CCS6 302 32278 S231 T S L A L D E S L F R G R Q I
Rat Rattus norvegicus B0BNE4 269 29843 R198 S S V Q A A V R L D E S T F R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520509 318 35286 S247 T S M A L D E S L F R G R Q I
Chicken Gallus gallus XP_001232211 249 27885 D178 V K A A V E L D E S I F R G R
Frog Xenopus laevis Q7ZXB8 295 32194 S225 T S L A L D E S L F R G R Q I
Zebra Danio Brachydanio rerio NP_001098602 232 25663 S161 T A M A L D E S L F R G R Q I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q7KNF2 224 24959 A153 S K E F V E T A L A M N E T L
Honey Bee Apis mellifera XP_393066 228 25717 A157 E R D S V Q T A M A M D E S M
Nematode Worm Caenorhab. elegans Q09295 191 21008 R121 V M N G S L F R S R P I V V T
Sea Urchin Strong. purpuratus XP_799120 247 26565 S165 T A C T L N L S L F K G R Q I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.4 N.A. 64.5 N.A. 96.7 38.2 N.A. 65.4 45.4 69.6 62 N.A. 45.7 46.4 25.1 45.4
Protein Similarity: 100 96.4 N.A. 68.7 N.A. 97.7 49.6 N.A. 69.5 56.2 75.8 68.9 N.A. 54.9 58.8 35.6 54.5
P-Site Identity: 100 6.6 N.A. 100 N.A. 100 13.3 N.A. 93.3 13.3 100 86.6 N.A. 6.6 0 0 60
P-Site Similarity: 100 26.6 N.A. 100 N.A. 100 26.6 N.A. 100 26.6 100 100 N.A. 40 33.3 0 80
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 16 16 54 8 8 0 16 0 16 0 0 0 0 0 % A
% Cys: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 8 0 0 47 0 8 8 8 0 8 0 0 0 % D
% Glu: 8 0 8 0 0 24 47 0 8 0 16 0 16 0 0 % E
% Phe: 0 8 0 8 0 0 16 0 0 54 0 8 0 8 0 % F
% Gly: 8 0 0 8 0 0 0 0 0 0 0 54 0 8 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 8 0 0 0 0 0 8 8 0 0 54 % I
% Lys: 0 16 0 0 0 0 0 0 0 8 8 0 0 0 0 % K
% Leu: 0 0 31 0 54 8 16 0 70 0 0 0 0 0 8 % L
% Met: 0 8 16 0 0 0 0 0 8 0 16 0 0 0 8 % M
% Asn: 0 0 8 0 0 8 0 0 0 0 0 8 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % P
% Gln: 0 0 0 8 0 8 0 0 0 0 0 0 0 54 0 % Q
% Arg: 0 8 0 0 0 0 0 16 0 8 47 0 62 8 16 % R
% Ser: 16 47 0 8 8 0 0 62 8 8 0 16 0 8 0 % S
% Thr: 54 0 0 8 0 0 16 0 0 0 0 0 8 8 16 % T
% Val: 16 0 8 0 24 0 8 0 0 0 0 0 16 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _