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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADCK1
All Species:
25.45
Human Site:
S490
Identified Species:
43.08
UniProt:
Q86TW2
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86TW2
NP_065154.2
530
60577
S490
F
F
R
R
T
Q
I
S
F
S
E
A
F
N
L
Chimpanzee
Pan troglodytes
XP_510098
657
73866
S617
F
F
R
R
T
Q
I
S
F
S
E
A
F
N
L
Rhesus Macaque
Macaca mulatta
XP_001104139
523
59652
S483
F
F
R
R
T
Q
I
S
F
R
E
A
F
N
L
Dog
Lupus familis
XP_547933
767
85798
S727
F
F
R
R
T
Q
I
S
F
R
E
A
F
N
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9D0L4
525
59717
S483
F
F
R
R
T
Q
I
S
F
S
E
A
F
S
L
Rat
Rattus norvegicus
NP_001102455
455
51692
A445
R
L
A
C
W
V
S
A
L
L
G
W
L
T
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505392
386
43627
L377
L
G
N
C
I
I
V
L
L
S
W
L
S
P
A
Chicken
Gallus gallus
Q5ZMT7
519
59182
S480
L
Y
R
R
V
H
I
S
L
T
E
A
L
S
L
Frog
Xenopus laevis
Q6INL7
520
59525
S483
L
W
S
Y
I
H
I
S
L
S
E
T
F
C
L
Zebra Danio
Brachydanio rerio
NP_001116521
521
59695
W482
R
S
R
R
V
R
I
W
L
S
E
R
W
S
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611947
518
59841
W484
S
G
S
S
R
I
L
W
L
R
V
R
E
R
W
Honey Bee
Apis mellifera
XP_392396
516
58880
S483
V
W
E
K
W
K
I
S
L
S
K
Q
W
A
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O04212
538
60900
W510
L
M
K
W
L
K
V
W
F
E
G
F
S
V
E
Baker's Yeast
Sacchar. cerevisiae
Q06567
569
65899
K530
E
Y
A
R
W
S
I
K
W
M
W
E
N
L
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.3
97.1
58.1
N.A.
87.3
74.1
N.A.
54.7
75.2
62.6
69
N.A.
44.7
45.8
N.A.
N.A.
Protein Similarity:
100
79.5
98.1
63
N.A.
93
80.1
N.A.
63.4
87.7
79.4
81.1
N.A.
65.4
64.3
N.A.
N.A.
P-Site Identity:
100
100
93.3
93.3
N.A.
93.3
0
N.A.
6.6
46.6
40
40
N.A.
0
26.6
N.A.
N.A.
P-Site Similarity:
100
100
93.3
93.3
N.A.
100
6.6
N.A.
13.3
66.6
46.6
60
N.A.
6.6
60
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
36.8
30
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
58.7
49
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
15
0
0
0
0
8
0
0
0
43
0
8
8
% A
% Cys:
0
0
0
15
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
8
0
8
0
0
0
0
0
0
8
58
8
8
0
8
% E
% Phe:
36
36
0
0
0
0
0
0
43
0
0
8
43
0
0
% F
% Gly:
0
15
0
0
0
0
0
0
0
0
15
0
0
0
0
% G
% His:
0
0
0
0
0
15
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
15
15
72
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
8
8
0
15
0
8
0
0
8
0
0
0
0
% K
% Leu:
29
8
0
0
8
0
8
8
50
8
0
8
15
8
65
% L
% Met:
0
8
0
0
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
0
0
0
0
0
0
0
8
29
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% P
% Gln:
0
0
0
0
0
36
0
0
0
0
0
8
0
0
0
% Q
% Arg:
15
0
50
58
8
8
0
0
0
22
0
15
0
8
8
% R
% Ser:
8
8
15
8
0
8
8
58
0
50
0
0
15
22
0
% S
% Thr:
0
0
0
0
36
0
0
0
0
8
0
8
0
8
8
% T
% Val:
8
0
0
0
15
8
15
0
0
0
8
0
0
8
0
% V
% Trp:
0
15
0
8
22
0
0
22
8
0
15
8
15
0
8
% W
% Tyr:
0
15
0
8
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _