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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADCK1
All Species:
34.85
Human Site:
S372
Identified Species:
58.97
UniProt:
Q86TW2
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86TW2
NP_065154.2
530
60577
S372
M
K
R
V
K
E
Y
S
Q
R
L
G
A
G
D
Chimpanzee
Pan troglodytes
XP_510098
657
73866
S499
M
K
R
V
K
E
Y
S
Q
R
L
G
A
G
D
Rhesus Macaque
Macaca mulatta
XP_001104139
523
59652
S365
M
K
R
V
K
E
Y
S
Q
R
L
G
A
G
D
Dog
Lupus familis
XP_547933
767
85798
S609
M
K
R
V
K
K
Y
S
Q
R
L
G
A
G
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9D0L4
525
59717
S365
M
D
G
L
K
Q
Y
S
Q
R
L
G
A
A
D
Rat
Rattus norvegicus
NP_001102455
455
51692
A328
V
K
Q
G
I
G
Q
A
P
V
S
A
T
E
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505392
386
43627
P260
N
K
G
I
G
R
S
P
V
T
A
S
E
D
V
Chicken
Gallus gallus
Q5ZMT7
519
59182
S362
M
K
R
V
Q
K
Y
S
R
R
L
G
A
G
D
Frog
Xenopus laevis
Q6INL7
520
59525
S365
K
E
R
I
R
I
Y
S
Q
R
L
G
A
G
E
Zebra Danio
Brachydanio rerio
NP_001116521
521
59695
S364
L
K
G
I
E
R
Y
S
R
R
L
G
A
G
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611947
518
59841
E366
K
A
M
R
Q
H
S
E
Q
L
G
I
K
G
D
Honey Bee
Apis mellifera
XP_392396
516
58880
C365
K
T
A
M
Q
T
H
C
A
N
L
G
V
T
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O04212
538
60900
S388
A
K
A
I
K
E
H
S
E
K
L
G
A
G
D
Baker's Yeast
Sacchar. cerevisiae
Q06567
569
65899
Y406
D
Q
T
K
M
K
K
Y
A
K
G
F
A
N
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.3
97.1
58.1
N.A.
87.3
74.1
N.A.
54.7
75.2
62.6
69
N.A.
44.7
45.8
N.A.
N.A.
Protein Similarity:
100
79.5
98.1
63
N.A.
93
80.1
N.A.
63.4
87.7
79.4
81.1
N.A.
65.4
64.3
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
66.6
13.3
N.A.
6.6
80
60
60
N.A.
20
20
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
80
33.3
N.A.
13.3
100
86.6
86.6
N.A.
26.6
40
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
36.8
30
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
58.7
49
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
60
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
86.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
15
0
0
0
0
8
15
0
8
8
72
8
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
8
8
0
0
0
0
0
0
0
0
0
0
0
8
79
% D
% Glu:
0
8
0
0
8
29
0
8
8
0
0
0
8
8
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% F
% Gly:
0
0
22
8
8
8
0
0
0
0
15
72
0
65
0
% G
% His:
0
0
0
0
0
8
15
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
29
8
8
0
0
0
0
0
8
0
0
8
% I
% Lys:
22
65
0
8
43
22
8
0
0
15
0
0
8
0
0
% K
% Leu:
8
0
0
8
0
0
0
0
0
8
72
0
0
0
0
% L
% Met:
43
0
8
8
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
0
0
0
8
0
0
0
8
0
% N
% Pro:
0
0
0
0
0
0
0
8
8
0
0
0
0
0
0
% P
% Gln:
0
8
8
0
22
8
8
0
50
0
0
0
0
0
0
% Q
% Arg:
0
0
43
8
8
15
0
0
15
58
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
15
65
0
0
8
8
0
0
0
% S
% Thr:
0
8
8
0
0
8
0
0
0
8
0
0
8
8
0
% T
% Val:
8
0
0
36
0
0
0
0
8
8
0
0
8
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
58
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _