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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADCK1
All Species:
37.88
Human Site:
S193
Identified Species:
64.1
UniProt:
Q86TW2
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86TW2
NP_065154.2
530
60577
S193
H
P
K
V
R
A
Q
S
S
K
D
I
L
L
M
Chimpanzee
Pan troglodytes
XP_510098
657
73866
S320
H
P
K
V
R
A
Q
S
S
K
D
I
L
L
M
Rhesus Macaque
Macaca mulatta
XP_001104139
523
59652
S186
H
P
K
V
R
A
Q
S
S
K
D
I
L
L
M
Dog
Lupus familis
XP_547933
767
85798
S430
H
P
K
V
Q
A
Q
S
S
K
D
I
L
L
M
Cat
Felis silvestris
Mouse
Mus musculus
Q9D0L4
525
59717
S186
H
P
K
V
Q
A
Q
S
S
K
D
I
L
L
M
Rat
Rattus norvegicus
NP_001102455
455
51692
S188
P
Q
I
H
W
E
L
S
T
K
R
V
L
L
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505392
386
43627
K135
K
G
L
K
V
N
L
K
E
F
L
P
D
M
E
Chicken
Gallus gallus
Q5ZMT7
519
59182
S183
H
P
K
V
Q
A
Q
S
S
K
D
I
F
L
M
Frog
Xenopus laevis
Q6INL7
520
59525
S186
H
P
K
V
Q
A
Q
S
S
R
D
I
L
I
M
Zebra Danio
Brachydanio rerio
NP_001116521
521
59695
S185
H
P
K
V
Q
R
Q
S
S
K
D
I
V
V
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611947
518
59841
S187
H
P
Y
V
K
G
N
S
R
V
D
M
K
T
M
Honey Bee
Apis mellifera
XP_392396
516
58880
S188
H
R
S
V
K
T
N
S
Y
V
D
I
K
T
M
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O04212
538
60900
A197
H
A
H
M
T
D
T
A
A
A
D
T
A
A
V
Baker's Yeast
Sacchar. cerevisiae
Q06567
569
65899
L216
V
K
C
Q
H
P
S
L
K
E
F
I
P
L
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.3
97.1
58.1
N.A.
87.3
74.1
N.A.
54.7
75.2
62.6
69
N.A.
44.7
45.8
N.A.
N.A.
Protein Similarity:
100
79.5
98.1
63
N.A.
93
80.1
N.A.
63.4
87.7
79.4
81.1
N.A.
65.4
64.3
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
93.3
33.3
N.A.
0
86.6
80
73.3
N.A.
40
40
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
46.6
N.A.
6.6
93.3
100
93.3
N.A.
53.3
46.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
36.8
30
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
58.7
49
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
50
0
8
8
8
0
0
8
8
0
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
8
0
0
0
0
79
0
8
0
8
% D
% Glu:
0
0
0
0
0
8
0
0
8
8
0
0
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
8
8
0
8
0
0
% F
% Gly:
0
8
0
0
0
8
0
0
0
0
0
0
0
0
0
% G
% His:
79
0
8
8
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
0
0
0
0
0
72
0
8
0
% I
% Lys:
8
8
58
8
15
0
0
8
8
58
0
0
15
0
0
% K
% Leu:
0
0
8
0
0
0
15
8
0
0
8
0
50
58
0
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
8
0
8
79
% M
% Asn:
0
0
0
0
0
8
15
0
0
0
0
0
0
0
0
% N
% Pro:
8
65
0
0
0
8
0
0
0
0
0
8
8
0
0
% P
% Gln:
0
8
0
8
36
0
58
0
0
0
0
0
0
0
0
% Q
% Arg:
0
8
0
0
22
8
0
0
8
8
8
0
0
0
0
% R
% Ser:
0
0
8
0
0
0
8
79
58
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
8
8
8
0
8
0
0
8
0
15
0
% T
% Val:
8
0
0
72
8
0
0
0
0
15
0
8
8
8
8
% V
% Trp:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _