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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADCK1
All Species:
4.55
Human Site:
S127
Identified Species:
7.69
UniProt:
Q86TW2
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86TW2
NP_065154.2
530
60577
S127
S
T
L
K
V
L
H
S
Q
A
P
Q
S
S
M
Chimpanzee
Pan troglodytes
XP_510098
657
73866
M261
S
Q
A
P
Q
S
S
M
Q
E
I
R
Q
V
I
Rhesus Macaque
Macaca mulatta
XP_001104139
523
59652
M127
S
Q
A
P
Q
S
S
M
Q
E
I
R
Q
V
I
Dog
Lupus familis
XP_547933
767
85798
S364
S
T
L
K
V
L
H
S
Q
A
P
Q
S
S
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9D0L4
525
59717
M127
S
Q
A
P
Q
S
S
M
Q
E
V
R
Q
V
I
Rat
Rattus norvegicus
NP_001102455
455
51692
V127
K
D
I
L
L
M
E
V
L
V
L
A
V
K
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505392
386
43627
E76
E
F
M
W
L
V
D
E
A
K
K
N
L
P
L
Chicken
Gallus gallus
Q5ZMT7
519
59182
R124
S
Q
A
P
Q
S
T
R
Q
E
I
E
Q
V
I
Frog
Xenopus laevis
Q6INL7
520
59525
F127
S
Q
A
P
C
T
P
F
T
D
V
V
Q
V
I
Zebra Danio
Brachydanio rerio
NP_001116521
521
59695
M126
S
R
A
P
H
S
S
M
E
H
I
R
Q
V
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611947
518
59841
I128
S
D
A
P
Q
N
P
I
E
D
L
Y
K
V
I
Honey Bee
Apis mellifera
XP_392396
516
58880
F129
S
S
A
P
Q
S
S
F
K
D
I
L
T
V
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O04212
538
60900
L130
R
T
M
R
E
S
M
L
N
K
C
P
I
S
S
Baker's Yeast
Sacchar. cerevisiae
Q06567
569
65899
D150
D
T
M
I
P
L
Q
D
H
C
P
E
S
T
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.3
97.1
58.1
N.A.
87.3
74.1
N.A.
54.7
75.2
62.6
69
N.A.
44.7
45.8
N.A.
N.A.
Protein Similarity:
100
79.5
98.1
63
N.A.
93
80.1
N.A.
63.4
87.7
79.4
81.1
N.A.
65.4
64.3
N.A.
N.A.
P-Site Identity:
100
13.3
13.3
93.3
N.A.
13.3
0
N.A.
0
13.3
6.6
6.6
N.A.
6.6
6.6
N.A.
N.A.
P-Site Similarity:
100
26.6
26.6
100
N.A.
26.6
20
N.A.
26.6
26.6
13.3
26.6
N.A.
20
33.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
36.8
30
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
58.7
49
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
58
0
0
0
0
0
8
15
0
8
0
0
0
% A
% Cys:
0
0
0
0
8
0
0
0
0
8
8
0
0
0
0
% C
% Asp:
8
15
0
0
0
0
8
8
0
22
0
0
0
0
0
% D
% Glu:
8
0
0
0
8
0
8
8
15
29
0
15
0
0
0
% E
% Phe:
0
8
0
0
0
0
0
15
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
8
0
15
0
8
8
0
0
0
0
0
% H
% Ile:
0
0
8
8
0
0
0
8
0
0
36
0
8
0
65
% I
% Lys:
8
0
0
15
0
0
0
0
8
15
8
0
8
8
0
% K
% Leu:
0
0
15
8
15
22
0
8
8
0
15
8
8
0
8
% L
% Met:
0
0
22
0
0
8
8
29
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
0
0
8
0
0
8
0
0
8
0
0
0
% N
% Pro:
0
0
0
58
8
0
15
0
0
0
22
8
0
8
0
% P
% Gln:
0
36
0
0
43
0
8
0
43
0
0
15
43
0
8
% Q
% Arg:
8
8
0
8
0
0
0
8
0
0
0
29
0
0
0
% R
% Ser:
72
8
0
0
0
50
36
15
0
0
0
0
22
22
8
% S
% Thr:
0
29
0
0
0
8
8
0
8
0
0
0
8
8
0
% T
% Val:
0
0
0
0
15
8
0
8
0
8
15
8
8
58
0
% V
% Trp:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _