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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ADCK1 All Species: 9.09
Human Site: S120 Identified Species: 15.38
UniProt: Q86TW2 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86TW2 NP_065154.2 530 60577 S120 L L P E E Y T S T L K V L H S
Chimpanzee Pan troglodytes XP_510098 657 73866 S254 S T L K V L H S Q A P Q S S M
Rhesus Macaque Macaca mulatta XP_001104139 523 59652 S120 S T L K V L H S Q A P Q S S M
Dog Lupus familis XP_547933 767 85798 S357 L L P E E Y T S T L K V L H S
Cat Felis silvestris
Mouse Mus musculus Q9D0L4 525 59717 S120 S T L K V L H S Q A P Q S S M
Rat Rattus norvegicus NP_001102455 455 51692 K120 K V Q A Q S S K D I L L M E V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505392 386 43627 E69 K Q L F P D F E F M W L V D E
Chicken Gallus gallus Q5ZMT7 519 59182 S117 R T L K V L H S Q A P Q S T R
Frog Xenopus laevis Q6INL7 520 59525 S120 K T L S V L H S Q A P C T P F
Zebra Danio Brachydanio rerio NP_001116521 521 59695 S119 S T L K I L H S R A P H S S M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611947 518 59841 S121 Q T M K V L H S D A P Q N P I
Honey Bee Apis mellifera XP_392396 516 58880 S122 N T M R V L H S S A P Q S S F
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O04212 538 60900 R123 L V P E E Y V R T M R E S M L
Baker's Yeast Sacchar. cerevisiae Q06567 569 65899 D143 L L P K E W T D T M I P L Q D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 79.3 97.1 58.1 N.A. 87.3 74.1 N.A. 54.7 75.2 62.6 69 N.A. 44.7 45.8 N.A. N.A.
Protein Similarity: 100 79.5 98.1 63 N.A. 93 80.1 N.A. 63.4 87.7 79.4 81.1 N.A. 65.4 64.3 N.A. N.A.
P-Site Identity: 100 6.6 6.6 100 N.A. 6.6 0 N.A. 0 6.6 6.6 6.6 N.A. 6.6 6.6 N.A. N.A.
P-Site Similarity: 100 13.3 13.3 100 N.A. 13.3 40 N.A. 20 13.3 6.6 13.3 N.A. 13.3 13.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 36.8 30 N.A.
Protein Similarity: N.A. N.A. N.A. 58.7 49 N.A.
P-Site Identity: N.A. N.A. N.A. 40 46.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 60 66.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 0 0 0 0 0 58 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % C
% Asp: 0 0 0 0 0 8 0 8 15 0 0 0 0 8 8 % D
% Glu: 0 0 0 22 29 0 0 8 0 0 0 8 0 8 8 % E
% Phe: 0 0 0 8 0 0 8 0 8 0 0 0 0 0 15 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 58 0 0 0 0 8 0 15 0 % H
% Ile: 0 0 0 0 8 0 0 0 0 8 8 0 0 0 8 % I
% Lys: 22 0 0 50 0 0 0 8 0 0 15 0 0 0 0 % K
% Leu: 29 22 50 0 0 58 0 0 0 15 8 15 22 0 8 % L
% Met: 0 0 15 0 0 0 0 0 0 22 0 0 8 8 29 % M
% Asn: 8 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % N
% Pro: 0 0 29 0 8 0 0 0 0 0 58 8 0 15 0 % P
% Gln: 8 8 8 0 8 0 0 0 36 0 0 43 0 8 0 % Q
% Arg: 8 0 0 8 0 0 0 8 8 0 8 0 0 0 8 % R
% Ser: 29 0 0 8 0 8 8 72 8 0 0 0 50 36 15 % S
% Thr: 0 58 0 0 0 0 22 0 29 0 0 0 8 8 0 % T
% Val: 0 15 0 0 50 0 8 0 0 0 0 15 8 0 8 % V
% Trp: 0 0 0 0 0 8 0 0 0 0 8 0 0 0 0 % W
% Tyr: 0 0 0 0 0 22 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _