KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SETD3
All Species:
20.91
Human Site:
Y489
Identified Species:
46
UniProt:
Q86TU7
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86TU7
NP_115609.2
594
67257
Y489
A
A
V
N
R
E
Y
Y
R
Q
Q
M
E
E
K
Chimpanzee
Pan troglodytes
XP_522946
594
67230
Y489
A
A
V
N
R
E
Y
Y
R
Q
Q
M
E
E
K
Rhesus Macaque
Macaca mulatta
XP_001103370
595
67455
Y489
A
A
V
N
R
E
F
Y
R
Q
Q
M
E
E
K
Dog
Lupus familis
XP_547974
589
66391
Y489
A
A
A
N
R
E
H
Y
R
K
Q
M
Q
A
G
Cat
Felis silvestris
Mouse
Mus musculus
Q91WC0
594
67158
Y489
A
A
V
N
R
E
Y
Y
R
K
H
M
E
E
R
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512656
355
39998
Y262
E
G
S
P
L
P
K
Y
E
E
S
N
I
A
L
Chicken
Gallus gallus
Q5ZML9
593
67177
Y489
A
A
A
S
R
E
Y
Y
T
K
Q
M
A
D
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_956348
596
67232
F489
G
R
A
K
R
L
H
F
Q
K
Q
L
D
E
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393639
457
52653
P363
L
L
N
K
L
D
L
P
T
V
G
E
F
L
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798530
682
75899
E508
E
V
K
R
E
E
D
E
G
V
V
V
E
K
W
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9XI84
482
54593
L389
V
S
R
T
N
E
E
L
I
C
R
V
V
R
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
98.6
90
N.A.
91.4
N.A.
N.A.
49.4
85.3
N.A.
70.6
N.A.
N.A.
32.4
N.A.
36.2
Protein Similarity:
100
99.8
99.5
94.7
N.A.
94.4
N.A.
N.A.
53.7
92.5
N.A.
84.7
N.A.
N.A.
47.6
N.A.
56.8
P-Site Identity:
100
100
93.3
60
N.A.
80
N.A.
N.A.
6.6
53.3
N.A.
20
N.A.
N.A.
0
N.A.
13.3
P-Site Similarity:
100
100
100
80
N.A.
93.3
N.A.
N.A.
13.3
73.3
N.A.
60
N.A.
N.A.
6.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
55
55
28
0
0
0
0
0
0
0
0
0
10
19
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
10
10
0
0
0
0
0
10
10
10
% D
% Glu:
19
0
0
0
10
73
10
10
10
10
0
10
46
46
0
% E
% Phe:
0
0
0
0
0
0
10
10
0
0
0
0
10
0
0
% F
% Gly:
10
10
0
0
0
0
0
0
10
0
10
0
0
0
28
% G
% His:
0
0
0
0
0
0
19
0
0
0
10
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
10
0
0
0
10
0
0
% I
% Lys:
0
0
10
19
0
0
10
0
0
37
0
0
0
10
28
% K
% Leu:
10
10
0
0
19
10
10
10
0
0
0
10
0
10
19
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
55
0
0
0
% M
% Asn:
0
0
10
46
10
0
0
0
0
0
0
10
0
0
0
% N
% Pro:
0
0
0
10
0
10
0
10
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
10
28
55
0
10
0
0
% Q
% Arg:
0
10
10
10
64
0
0
0
46
0
10
0
0
10
10
% R
% Ser:
0
10
10
10
0
0
0
0
0
0
10
0
0
0
0
% S
% Thr:
0
0
0
10
0
0
0
0
19
0
0
0
0
0
0
% T
% Val:
10
10
37
0
0
0
0
0
0
19
10
19
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% W
% Tyr:
0
0
0
0
0
0
37
64
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _