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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SETD3
All Species:
31.21
Human Site:
T130
Identified Species:
68.67
UniProt:
Q86TU7
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86TU7
NP_115609.2
594
67257
T130
V
P
R
K
L
L
M
T
V
E
S
A
K
N
S
Chimpanzee
Pan troglodytes
XP_522946
594
67230
T130
V
P
R
K
L
L
M
T
V
E
S
A
K
N
S
Rhesus Macaque
Macaca mulatta
XP_001103370
595
67455
T130
V
P
R
K
L
L
M
T
V
E
S
A
K
N
S
Dog
Lupus familis
XP_547974
589
66391
T130
V
P
R
K
L
L
M
T
V
E
S
A
K
N
S
Cat
Felis silvestris
Mouse
Mus musculus
Q91WC0
594
67158
T130
V
P
R
K
L
L
M
T
V
E
S
A
K
N
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512656
355
39998
Chicken
Gallus gallus
Q5ZML9
593
67177
T130
V
P
R
K
L
L
M
T
V
E
S
A
K
N
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_956348
596
67232
T130
I
P
R
K
M
L
M
T
V
E
S
A
K
N
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393639
457
52653
R27
R
Q
L
S
L
A
K
R
N
E
I
N
A
L
C
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798530
682
75899
T130
I
P
R
K
V
M
M
T
D
Q
N
A
V
D
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9XI84
482
54593
W53
P
E
N
V
R
N
F
W
K
W
L
R
D
Q
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
98.6
90
N.A.
91.4
N.A.
N.A.
49.4
85.3
N.A.
70.6
N.A.
N.A.
32.4
N.A.
36.2
Protein Similarity:
100
99.8
99.5
94.7
N.A.
94.4
N.A.
N.A.
53.7
92.5
N.A.
84.7
N.A.
N.A.
47.6
N.A.
56.8
P-Site Identity:
100
100
100
100
N.A.
100
N.A.
N.A.
0
100
N.A.
86.6
N.A.
N.A.
13.3
N.A.
46.6
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
0
100
N.A.
100
N.A.
N.A.
13.3
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
0
0
0
0
0
73
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% C
% Asp:
0
0
0
0
0
0
0
0
10
0
0
0
10
10
0
% D
% Glu:
0
10
0
0
0
0
0
0
0
73
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
19
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% I
% Lys:
0
0
0
73
0
0
10
0
10
0
0
0
64
0
0
% K
% Leu:
0
0
10
0
64
64
0
0
0
0
10
0
0
10
0
% L
% Met:
0
0
0
0
10
10
73
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
10
0
0
10
0
10
10
0
64
0
% N
% Pro:
10
73
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
10
0
0
0
0
0
0
0
10
0
0
0
10
0
% Q
% Arg:
10
0
73
0
10
0
0
10
0
0
0
10
0
0
0
% R
% Ser:
0
0
0
10
0
0
0
0
0
0
64
0
0
0
73
% S
% Thr:
0
0
0
0
0
0
0
73
0
0
0
0
0
0
0
% T
% Val:
55
0
0
10
10
0
0
0
64
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
10
0
10
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _