Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATG4D All Species: 22.73
Human Site: T394 Identified Species: 35.71
UniProt: Q86TL0 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86TL0 NP_116274.3 474 52922 T394 A K M D P S C T V G F Y A G D
Chimpanzee Pan troglodytes XP_512373 411 46398 V332 K M D P S C T V G F Y A G D R
Rhesus Macaque Macaca mulatta XP_001101860 474 52893 T394 A K M D P S C T V G F Y A G D
Dog Lupus familis XP_542069 473 52729 T393 A K M D P S C T V G F Y A G D
Cat Felis silvestris
Mouse Mus musculus Q8BGV9 474 52892 T394 A K M D P S C T V G F Y A G N
Rat Rattus norvegicus NP_001094483 473 52805 T393 A K M D P S C T V G F Y A G N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514370 459 52127 K372 F H C P S P K K M S F R K M D
Chicken Gallus gallus Q6PZ02 393 44512 D314 R M S I A E L D P S I A V G F
Frog Xenopus laevis Q68FJ9 469 52793 S380 L E S F H C N S P R K I S I T
Zebra Danio Brachydanio rerio Q6DG88 394 44435 L315 C R M H I C E L D P S I A A G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650452 668 74736 C548 S K M D P S C C I G F Y C A T
Honey Bee Apis mellifera XP_393739 477 54008 C396 S K M D P S C C V G F Y F H N
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786847 723 81931 T638 S K M D P S C T I G F Y I R T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8S929 467 51510 E357 T Y I V G V Q E D K G F Y L D
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7S3X7 506 55337 R427 E L D T C H T R R L R Q L H I
Conservation
Percent
Protein Identity: 100 84.8 98.5 94.3 N.A. 86.2 86.7 N.A. 44 26.5 53.3 27 N.A. 30.3 35 N.A. 30.8
Protein Similarity: 100 85.6 98.9 96.1 N.A. 90.9 91.1 N.A. 59.4 39.6 68.9 41.9 N.A. 44.4 49.2 N.A. 41.9
P-Site Identity: 100 0 100 100 N.A. 93.3 93.3 N.A. 13.3 6.6 0 13.3 N.A. 60 66.6 N.A. 66.6
P-Site Similarity: 100 6.6 100 100 N.A. 100 100 N.A. 20 6.6 20 20 N.A. 73.3 80 N.A. 80
Percent
Protein Identity: N.A. N.A. N.A. 27.4 N.A. 22.1
Protein Similarity: N.A. N.A. N.A. 42.4 N.A. 36.3
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. 0
P-Site Similarity: N.A. N.A. N.A. 20 N.A. 0
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 34 0 0 0 7 0 0 0 0 0 0 14 40 14 0 % A
% Cys: 7 0 7 0 7 20 54 14 0 0 0 0 7 0 0 % C
% Asp: 0 0 14 54 0 0 0 7 14 0 0 0 0 7 34 % D
% Glu: 7 7 0 0 0 7 7 7 0 0 0 0 0 0 0 % E
% Phe: 7 0 0 7 0 0 0 0 0 7 60 7 7 0 7 % F
% Gly: 0 0 0 0 7 0 0 0 7 54 7 0 7 40 7 % G
% His: 0 7 0 7 7 7 0 0 0 0 0 0 0 14 0 % H
% Ile: 0 0 7 7 7 0 0 0 14 0 7 14 7 7 7 % I
% Lys: 7 54 0 0 0 0 7 7 0 7 7 0 7 0 0 % K
% Leu: 7 7 0 0 0 0 7 7 0 7 0 0 7 7 0 % L
% Met: 0 14 60 0 0 0 0 0 7 0 0 0 0 7 0 % M
% Asn: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 20 % N
% Pro: 0 0 0 14 54 7 0 0 14 7 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 7 0 0 0 0 7 0 0 0 % Q
% Arg: 7 7 0 0 0 0 0 7 7 7 7 7 0 7 7 % R
% Ser: 20 0 14 0 14 54 0 7 0 14 7 0 7 0 0 % S
% Thr: 7 0 0 7 0 0 14 40 0 0 0 0 0 0 20 % T
% Val: 0 0 0 7 0 7 0 7 40 0 0 0 7 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 7 0 0 0 0 0 0 0 0 7 54 7 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _