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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATG4D
All Species:
12.42
Human Site:
T167
Identified Species:
19.52
UniProt:
Q86TL0
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86TL0
NP_116274.3
474
52922
T167
H
F
L
P
R
D
W
T
W
A
E
G
M
G
L
Chimpanzee
Pan troglodytes
XP_512373
411
46398
P134
G
P
A
R
W
M
P
P
R
W
A
Q
G
A
P
Rhesus Macaque
Macaca mulatta
XP_001101860
474
52893
T167
H
F
L
P
R
D
W
T
W
A
E
G
T
G
L
Dog
Lupus familis
XP_542069
473
52729
T166
H
F
L
P
R
D
W
T
W
A
E
G
P
G
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGV9
474
52892
R167
H
F
L
P
R
D
W
R
W
V
E
G
T
G
L
Rat
Rattus norvegicus
NP_001094483
473
52805
R166
H
F
L
P
R
D
W
R
W
V
E
G
T
G
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514370
459
52127
A159
H
T
V
K
K
L
T
A
S
F
E
A
S
W
V
Chicken
Gallus gallus
Q6PZ02
393
44512
I115
F
S
V
L
N
A
F
I
D
K
K
D
S
Y
Y
Frog
Xenopus laevis
Q68FJ9
469
52793
T154
H
L
L
S
R
E
W
T
W
S
E
A
L
Y
R
Zebra Danio
Brachydanio rerio
Q6DG88
394
44435
D117
S
I
L
N
A
F
I
D
K
K
D
S
Y
Y
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650452
668
74736
N335
L
H
S
T
Y
E
D
N
M
H
K
K
I
V
K
Honey Bee
Apis mellifera
XP_393739
477
54008
G187
A
L
V
C
H
F
L
G
R
E
W
R
W
Q
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786847
723
81931
S418
G
W
G
C
M
L
R
S
G
Q
M
M
L
A
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8S929
467
51510
K152
K
I
L
M
T
Y
R
K
G
F
E
P
F
R
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7S3X7
506
55337
G223
T
G
F
S
S
D
T
G
W
G
C
M
I
R
S
Conservation
Percent
Protein Identity:
100
84.8
98.5
94.3
N.A.
86.2
86.7
N.A.
44
26.5
53.3
27
N.A.
30.3
35
N.A.
30.8
Protein Similarity:
100
85.6
98.9
96.1
N.A.
90.9
91.1
N.A.
59.4
39.6
68.9
41.9
N.A.
44.4
49.2
N.A.
41.9
P-Site Identity:
100
0
93.3
93.3
N.A.
80
80
N.A.
13.3
0
46.6
6.6
N.A.
0
0
N.A.
0
P-Site Similarity:
100
0
93.3
93.3
N.A.
80
80
N.A.
33.3
20
66.6
13.3
N.A.
20
6.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.4
N.A.
22.1
Protein Similarity:
N.A.
N.A.
N.A.
42.4
N.A.
36.3
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
7
0
7
7
0
7
0
20
7
14
0
14
0
% A
% Cys:
0
0
0
14
0
0
0
0
0
0
7
0
0
0
0
% C
% Asp:
0
0
0
0
0
40
7
7
7
0
7
7
0
0
7
% D
% Glu:
0
0
0
0
0
14
0
0
0
7
54
0
0
0
0
% E
% Phe:
7
34
7
0
0
14
7
0
0
14
0
0
7
0
0
% F
% Gly:
14
7
7
0
0
0
0
14
14
7
0
34
7
34
0
% G
% His:
47
7
0
0
7
0
0
0
0
7
0
0
0
0
7
% H
% Ile:
0
14
0
0
0
0
7
7
0
0
0
0
14
0
0
% I
% Lys:
7
0
0
7
7
0
0
7
7
14
14
7
0
0
7
% K
% Leu:
7
14
54
7
0
14
7
0
0
0
0
0
14
0
34
% L
% Met:
0
0
0
7
7
7
0
0
7
0
7
14
7
0
0
% M
% Asn:
0
0
0
7
7
0
0
7
0
0
0
0
0
0
0
% N
% Pro:
0
7
0
34
0
0
7
7
0
0
0
7
7
0
14
% P
% Gln:
0
0
0
0
0
0
0
0
0
7
0
7
0
7
0
% Q
% Arg:
0
0
0
7
40
0
14
14
14
0
0
7
0
14
7
% R
% Ser:
7
7
7
14
7
0
0
7
7
7
0
7
14
0
14
% S
% Thr:
7
7
0
7
7
0
14
27
0
0
0
0
20
0
0
% T
% Val:
0
0
20
0
0
0
0
0
0
14
0
0
0
7
7
% V
% Trp:
0
7
0
0
7
0
40
0
47
7
7
0
7
7
0
% W
% Tyr:
0
0
0
0
7
7
0
0
0
0
0
0
7
20
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _