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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RALYL All Species: 18.79
Human Site: S212 Identified Species: 51.67
UniProt: Q86SE5 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86SE5 NP_001093861.1 291 32331 S212 Q I K T K I D S L L G R L E K
Chimpanzee Pan troglodytes XP_001163822 417 46000 G341 T K I D S L L G R L E K I E K
Rhesus Macaque Macaca mulatta XP_001094681 218 24798 E163 E A Q K K Q L E E S L V L I Q
Dog Lupus familis XP_544154 293 32545 S214 Q I K T K I D S L L G R L E K
Cat Felis silvestris
Mouse Mus musculus Q8BTF8 293 32433 S214 Q I K T K I D S L L G R L E K
Rat Rattus norvegicus NP_001011958 295 31031 S211 D G K K K G D S S S G G G G G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507284 302 33319 S214 Q I K T K I D S L L G R L E K
Chicken Gallus gallus XP_418314 249 28042 A195 K K Q M E D N A D L I Q E E C
Frog Xenopus laevis P19600 282 30931 S196 Q I K Q R V D S L L E N L E R
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 66.1 73.1 96.5 N.A. 94.8 37.9 N.A. 88.7 41.2 49.4 N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 66.4 74.5 98.2 N.A. 97.2 48.8 N.A. 93.7 52.5 60.8 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 20 13.3 100 N.A. 100 33.3 N.A. 100 13.3 60 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 40 33.3 100 N.A. 100 33.3 N.A. 100 53.3 80 N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 12 0 0 0 0 0 12 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12 % C
% Asp: 12 0 0 12 0 12 67 0 12 0 0 0 0 0 0 % D
% Glu: 12 0 0 0 12 0 0 12 12 0 23 0 12 78 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 12 0 0 0 12 0 12 0 0 56 12 12 12 12 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 56 12 0 0 45 0 0 0 0 12 0 12 12 0 % I
% Lys: 12 23 67 23 67 0 0 0 0 0 0 12 0 0 56 % K
% Leu: 0 0 0 0 0 12 23 0 56 78 12 0 67 0 0 % L
% Met: 0 0 0 12 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 12 0 0 0 0 12 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 56 0 23 12 0 12 0 0 0 0 0 12 0 0 12 % Q
% Arg: 0 0 0 0 12 0 0 0 12 0 0 45 0 0 12 % R
% Ser: 0 0 0 0 12 0 0 67 12 23 0 0 0 0 0 % S
% Thr: 12 0 0 45 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 12 0 0 0 0 0 12 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _