KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PXK
All Species:
21.52
Human Site:
T504
Identified Species:
39.44
UniProt:
Q7Z7A4
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z7A4
NP_060241.2
578
64950
T504
L
T
S
P
S
S
P
T
P
P
S
T
S
G
I
Chimpanzee
Pan troglodytes
XP_001174144
580
65126
T504
L
T
S
P
S
S
P
T
P
P
S
T
S
G
I
Rhesus Macaque
Macaca mulatta
XP_001094947
468
53990
S400
L
L
Q
M
P
L
F
S
D
V
L
L
T
T
S
Dog
Lupus familis
XP_533779
498
56612
Q430
H
R
R
L
T
R
A
Q
S
H
H
G
S
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8BX57
582
65213
T504
L
T
S
P
S
S
P
T
P
P
S
T
A
G
L
Rat
Rattus norvegicus
Q4FZZ1
580
65080
T504
L
T
S
P
S
S
P
T
P
P
S
T
A
G
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506344
166
19503
A98
E
R
L
V
L
S
W
A
D
L
G
P
D
K
Y
Chicken
Gallus gallus
XP_414403
564
63568
P492
T
S
P
S
S
P
T
P
P
S
T
A
G
A
S
Frog
Xenopus laevis
NP_001090231
577
64854
P504
T
S
P
S
S
P
T
P
P
C
T
A
G
V
S
Zebra Danio
Brachydanio rerio
NP_001076277
575
64593
T506
P
T
C
P
S
S
P
T
P
L
P
G
S
G
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610341
646
71703
E565
N
R
S
D
S
T
P
E
E
P
T
T
L
A
G
Honey Bee
Apis mellifera
XP_392133
583
66076
S501
K
S
P
E
R
S
D
S
P
T
S
T
S
T
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783313
710
79220
T642
A
G
N
G
A
V
P
T
P
P
P
P
S
T
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
76.9
84.5
N.A.
92.2
92.4
N.A.
25.9
83.3
80.6
73.3
N.A.
35.9
42.8
N.A.
35.7
Protein Similarity:
100
99.6
78.5
85.2
N.A.
95.5
95.6
N.A.
27.6
90.4
89.6
85.4
N.A.
54
61
N.A.
50.8
P-Site Identity:
100
100
6.6
6.6
N.A.
86.6
86.6
N.A.
6.6
13.3
13.3
60
N.A.
33.3
33.3
N.A.
33.3
P-Site Similarity:
100
100
20
13.3
N.A.
100
100
N.A.
6.6
26.6
26.6
60
N.A.
46.6
46.6
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
8
0
8
8
0
0
0
16
16
16
16
% A
% Cys:
0
0
8
0
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
8
0
16
0
0
0
8
0
0
% D
% Glu:
8
0
0
8
0
0
0
8
8
0
0
0
0
8
8
% E
% Phe:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
8
0
0
0
0
0
0
8
16
16
39
8
% G
% His:
8
0
0
0
0
0
0
0
0
8
8
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
16
% I
% Lys:
8
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% K
% Leu:
39
8
8
8
8
8
0
0
0
16
8
8
8
0
16
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
8
0
24
39
8
16
54
16
70
47
16
16
0
0
8
% P
% Gln:
0
0
8
0
0
0
0
8
0
0
0
0
0
0
0
% Q
% Arg:
0
24
8
0
8
8
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
24
39
16
62
54
0
16
8
8
39
0
47
0
24
% S
% Thr:
16
39
0
0
8
8
16
47
0
8
24
47
8
24
0
% T
% Val:
0
0
0
8
0
8
0
0
0
8
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _