KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PXK
All Species:
21.52
Human Site:
S467
Identified Species:
39.44
UniProt:
Q7Z7A4
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z7A4
NP_060241.2
578
64950
S467
K
I
L
A
R
K
K
S
K
R
S
A
L
E
N
Chimpanzee
Pan troglodytes
XP_001174144
580
65126
S467
K
I
L
A
R
K
K
S
K
R
S
A
L
E
N
Rhesus Macaque
Macaca mulatta
XP_001094947
468
53990
P363
S
V
P
V
D
S
F
P
P
A
P
S
M
A
V
Dog
Lupus familis
XP_533779
498
56612
K393
T
S
E
K
P
Q
F
K
I
P
T
K
L
K
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8BX57
582
65213
S467
K
I
L
A
R
K
K
S
K
R
S
A
V
E
N
Rat
Rattus norvegicus
Q4FZZ1
580
65080
S467
K
I
L
A
R
K
K
S
K
R
S
A
V
E
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506344
166
19503
P61
S
M
F
F
R
S
E
P
K
W
E
V
V
E
P
Chicken
Gallus gallus
XP_414403
564
63568
S455
K
I
L
A
R
K
K
S
K
R
S
A
Y
E
S
Frog
Xenopus laevis
NP_001090231
577
64854
S467
K
I
L
A
R
K
K
S
K
R
T
N
C
D
T
Zebra Danio
Brachydanio rerio
NP_001076277
575
64593
K469
K
R
K
I
L
A
R
K
K
S
R
Q
S
T
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610341
646
71703
N528
Q
S
S
I
Q
T
N
N
G
R
L
S
L
V
A
Honey Bee
Apis mellifera
XP_392133
583
66076
K464
E
E
E
M
K
K
R
K
Q
K
L
K
K
E
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783313
710
79220
K605
D
E
E
K
R
R
R
K
K
A
H
L
K
K
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
76.9
84.5
N.A.
92.2
92.4
N.A.
25.9
83.3
80.6
73.3
N.A.
35.9
42.8
N.A.
35.7
Protein Similarity:
100
99.6
78.5
85.2
N.A.
95.5
95.6
N.A.
27.6
90.4
89.6
85.4
N.A.
54
61
N.A.
50.8
P-Site Identity:
100
100
0
6.6
N.A.
93.3
93.3
N.A.
20
86.6
66.6
13.3
N.A.
13.3
13.3
N.A.
13.3
P-Site Similarity:
100
100
20
26.6
N.A.
100
100
N.A.
40
93.3
80
20
N.A.
40
46.6
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
47
0
8
0
0
0
16
0
39
0
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
8
0
0
0
8
0
0
0
0
0
0
0
0
8
0
% D
% Glu:
8
16
24
0
0
0
8
0
0
0
8
0
0
54
8
% E
% Phe:
0
0
8
8
0
0
16
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
0
47
0
16
0
0
0
0
8
0
0
0
0
0
0
% I
% Lys:
54
0
8
16
8
54
47
31
70
8
0
16
16
16
0
% K
% Leu:
0
0
47
0
8
0
0
0
0
0
16
8
31
0
0
% L
% Met:
0
8
0
8
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
0
0
0
0
8
8
0
0
0
8
0
0
31
% N
% Pro:
0
0
8
0
8
0
0
16
8
8
8
0
0
0
8
% P
% Gln:
8
0
0
0
8
8
0
0
8
0
0
8
0
0
8
% Q
% Arg:
0
8
0
0
62
8
24
0
0
54
8
0
0
0
8
% R
% Ser:
16
16
8
0
0
16
0
47
0
8
39
16
8
0
8
% S
% Thr:
8
0
0
0
0
8
0
0
0
0
16
0
0
8
8
% T
% Val:
0
8
0
8
0
0
0
0
0
0
0
8
24
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _