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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PXK
All Species:
20.91
Human Site:
S190
Identified Species:
38.33
UniProt:
Q7Z7A4
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z7A4
NP_060241.2
578
64950
S190
L
G
P
D
K
Y
L
S
D
K
D
F
Q
C
L
Chimpanzee
Pan troglodytes
XP_001174144
580
65126
S190
L
G
P
D
K
Y
L
S
D
K
D
F
Q
C
L
Rhesus Macaque
Macaca mulatta
XP_001094947
468
53990
N106
Y
L
N
V
I
T
T
N
H
I
L
S
N
C
E
Dog
Lupus familis
XP_533779
498
56612
P134
P
K
W
E
V
V
E
P
L
K
D
I
G
W
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8BX57
582
65213
S190
L
G
P
D
K
Y
L
S
D
K
D
F
Q
C
L
Rat
Rattus norvegicus
Q4FZZ1
580
65080
S190
L
G
P
D
K
Y
L
S
D
K
D
F
Q
C
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506344
166
19503
Chicken
Gallus gallus
XP_414403
564
63568
S178
L
G
P
D
K
Y
L
S
D
K
D
L
Q
Y
A
Frog
Xenopus laevis
NP_001090231
577
64854
Q190
L
G
P
D
K
Y
L
Q
D
K
D
F
Q
C
A
Zebra Danio
Brachydanio rerio
NP_001076277
575
64593
S194
L
G
P
D
K
F
L
S
D
K
D
L
Q
S
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610341
646
71703
D229
Y
G
P
D
K
F
I
D
E
K
E
I
G
G
I
Honey Bee
Apis mellifera
XP_392133
583
66076
Q190
F
G
P
D
K
H
L
Q
D
K
D
M
Q
G
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783313
710
79220
D335
Y
G
P
D
K
D
L
D
Y
K
D
L
V
P
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
76.9
84.5
N.A.
92.2
92.4
N.A.
25.9
83.3
80.6
73.3
N.A.
35.9
42.8
N.A.
35.7
Protein Similarity:
100
99.6
78.5
85.2
N.A.
95.5
95.6
N.A.
27.6
90.4
89.6
85.4
N.A.
54
61
N.A.
50.8
P-Site Identity:
100
100
6.6
13.3
N.A.
100
100
N.A.
0
80
86.6
73.3
N.A.
33.3
60
N.A.
46.6
P-Site Similarity:
100
100
13.3
20
N.A.
100
100
N.A.
0
80
86.6
80
N.A.
66.6
73.3
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
24
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
47
0
% C
% Asp:
0
0
0
77
0
8
0
16
62
0
77
0
0
0
0
% D
% Glu:
0
0
0
8
0
0
8
0
8
0
8
0
0
0
8
% E
% Phe:
8
0
0
0
0
16
0
0
0
0
0
39
0
0
0
% F
% Gly:
0
77
0
0
0
0
0
0
0
0
0
0
16
16
0
% G
% His:
0
0
0
0
0
8
0
0
8
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
0
8
0
0
8
0
16
0
0
16
% I
% Lys:
0
8
0
0
77
0
0
0
0
85
0
0
0
0
0
% K
% Leu:
54
8
0
0
0
0
70
0
8
0
8
24
0
0
31
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
8
0
0
0
0
8
0
0
0
0
8
0
0
% N
% Pro:
8
0
77
0
0
0
0
8
0
0
0
0
0
8
0
% P
% Gln:
0
0
0
0
0
0
0
16
0
0
0
0
62
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% R
% Ser:
0
0
0
0
0
0
0
47
0
0
0
8
0
8
0
% S
% Thr:
0
0
0
0
0
8
8
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
8
8
8
0
0
0
0
0
0
8
0
8
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
0
0
8
0
% W
% Tyr:
24
0
0
0
0
47
0
0
8
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _