KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLN
All Species:
4.55
Human Site:
T591
Identified Species:
16.67
UniProt:
Q7Z5Q5
Number Species:
6
Phosphosite Substitution
Charge Score:
-0.5
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z5Q5
NP_861524.2
900
100307
T591
K
H
P
I
Q
I
T
T
P
K
N
F
K
G
K
Chimpanzee
Pan troglodytes
XP_001147229
900
100248
T591
K
H
P
I
Q
I
T
T
P
K
N
F
K
G
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_545922
947
106064
K591
K
H
P
I
K
I
T
K
P
Q
N
F
K
G
T
Cat
Felis silvestris
Mouse
Mus musculus
Q7TQ07
864
96657
K590
K
H
P
I
K
I
S
K
P
W
N
F
K
G
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420834
530
60155
L274
K
S
T
Y
V
D
G
L
R
T
C
M
R
K
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001093496
1146
129583
K870
K
L
P
L
Q
I
S
K
K
Q
Y
I
H
G
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790049
1312
146593
V876
K
D
A
N
G
S
V
V
N
E
S
T
V
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98
N.A.
70.1
N.A.
70.5
N.A.
N.A.
N.A.
36.5
N.A.
34.4
N.A.
N.A.
N.A.
N.A.
22.4
Protein Similarity:
100
98.8
N.A.
77.9
N.A.
79.4
N.A.
N.A.
N.A.
47.3
N.A.
51.2
N.A.
N.A.
N.A.
N.A.
36.6
P-Site Identity:
100
100
N.A.
73.3
N.A.
73.3
N.A.
N.A.
N.A.
6.6
N.A.
40
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
N.A.
86.6
N.A.
86.6
N.A.
N.A.
N.A.
13.3
N.A.
60
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
15
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
15
0
0
0
0
% C
% Asp:
0
15
0
0
0
15
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
15
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
58
0
0
0
% F
% Gly:
0
0
0
0
15
0
15
0
0
0
0
0
0
72
15
% G
% His:
0
58
0
0
0
0
0
0
0
0
0
0
15
0
0
% H
% Ile:
0
0
0
58
0
72
0
0
0
0
0
15
0
0
0
% I
% Lys:
100
0
0
0
29
0
0
43
15
29
0
0
58
15
58
% K
% Leu:
0
15
0
15
0
0
0
15
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
15
0
0
0
% M
% Asn:
0
0
0
15
0
0
0
0
15
0
58
0
0
0
0
% N
% Pro:
0
0
72
0
0
0
0
0
58
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
43
0
0
0
0
29
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
15
0
0
0
15
0
0
% R
% Ser:
0
15
0
0
0
15
29
0
0
0
15
0
0
15
15
% S
% Thr:
0
0
15
0
0
0
43
29
0
15
0
15
0
0
15
% T
% Val:
0
0
0
0
15
0
15
15
0
0
0
0
15
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
15
0
0
0
0
0
% W
% Tyr:
0
0
0
15
0
0
0
0
0
0
15
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _