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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ABHD12B All Species: 9.09
Human Site: S155 Identified Species: 15.38
UniProt: Q7Z5M8 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7Z5M8 NP_853511.2 362 40776 S155 S A E H R A A S H R L K L V K
Chimpanzee Pan troglodytes XP_522850 362 40684 S155 S A E H R A A S H R L K L V K
Rhesus Macaque Macaca mulatta XP_001102076 362 40830 S155 S A E H R A A S H R L K L V K
Dog Lupus familis XP_853408 370 41828 P163 S A E H R A A P H R L E L V K
Cat Felis silvestris
Mouse Mus musculus Q99LR1 398 45251 D184 N A G T R G G D H R V E L Y K
Rat Rattus norvegicus Q6AYT7 398 45277 D184 N A G T R G G D H R V E L Y K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515209 427 47963 N220 S A E N R A S N H R V K L M K
Chicken Gallus gallus Q5ZIN0 381 43837 D167 N A G T R G G D H R V E L Y K
Frog Xenopus laevis Q6IRP4 336 38243 R151 N L I L V D Y R G Y G K S D G
Zebra Danio Brachydanio rerio Q08C93 382 43267 D170 N A G T R G G D H R V Q L Y K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_725856 411 47343 G197 N T A S R G S G H R S E V Y K
Honey Bee Apis mellifera XP_395396 359 41457 R145 G N R A S S H R L E L Y K L F
Nematode Worm Caenorhab. elegans NP_505054 345 39613 V146 S D C N Y H V V C F D Y R G Y
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P42840 284 32290 I100 Y F I L I I D I F Y R Q F G M
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 95 79.7 N.A. 39.2 39.4 N.A. 59.4 38 21.5 36.9 N.A. 27.4 29.8 27.8 N.A.
Protein Similarity: 100 99.7 96.6 86.7 N.A. 56.2 56.5 N.A. 70.2 56.6 39.7 57.5 N.A. 45.2 52.4 47.5 N.A.
P-Site Identity: 100 100 100 86.6 N.A. 40 40 N.A. 66.6 40 6.6 40 N.A. 26.6 6.6 6.6 N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 60 60 N.A. 100 60 13.3 60 N.A. 53.3 20 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 22.1 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 37 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 65 8 8 0 36 29 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 8 0 0 0 0 0 8 0 0 0 0 0 0 % C
% Asp: 0 8 0 0 0 8 8 29 0 0 8 0 0 8 0 % D
% Glu: 0 0 36 0 0 0 0 0 0 8 0 36 0 0 0 % E
% Phe: 0 8 0 0 0 0 0 0 8 8 0 0 8 0 8 % F
% Gly: 8 0 29 0 0 36 29 8 8 0 8 0 0 15 8 % G
% His: 0 0 0 29 0 8 8 0 72 0 0 0 0 0 0 % H
% Ile: 0 0 15 0 8 8 0 8 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 36 8 0 72 % K
% Leu: 0 8 0 15 0 0 0 0 8 0 36 0 65 8 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 8 % M
% Asn: 43 8 0 15 0 0 0 8 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 15 0 0 0 % Q
% Arg: 0 0 8 0 72 0 0 15 0 72 8 0 8 0 0 % R
% Ser: 43 0 0 8 8 8 15 22 0 0 8 0 8 0 0 % S
% Thr: 0 8 0 29 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 8 0 8 8 0 0 36 0 8 29 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 0 8 0 8 0 0 15 0 15 0 36 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _