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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMC3
All Species:
15.15
Human Site:
T466
Identified Species:
47.62
UniProt:
Q7Z5M5
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z5M5
NP_001074001
1102
125868
T466
M
G
L
R
R
N
N
T
W
A
L
E
E
T
S
Chimpanzee
Pan troglodytes
XP_510545
1100
125812
T467
M
G
L
R
R
N
N
T
W
A
L
E
E
T
S
Rhesus Macaque
Macaca mulatta
XP_001110155
1100
125901
T467
M
G
L
R
R
N
S
T
W
A
L
E
E
T
S
Dog
Lupus familis
XP_545878
1132
128174
T467
I
G
L
G
R
N
S
T
W
G
P
D
E
T
S
Cat
Felis silvestris
Mouse
Mus musculus
Q7TQ69
1130
128673
S467
A
E
L
R
R
N
T
S
T
W
V
V
E
E
T
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5YCC7
1138
128744
H475
Q
M
N
S
S
E
S
H
A
Q
S
L
P
T
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_696187
1125
127519
P468
R
H
N
I
T
L
S
P
S
L
L
E
L
N
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q11069
1203
136041
G562
V
V
E
T
H
M
F
G
P
N
S
D
W
N
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98
96.3
79
N.A.
79.4
N.A.
N.A.
N.A.
65.3
N.A.
61.1
N.A.
N.A.
N.A.
29.5
N.A.
Protein Similarity:
100
99
98.1
85.9
N.A.
85.5
N.A.
N.A.
N.A.
76.9
N.A.
74
N.A.
N.A.
N.A.
47.1
N.A.
P-Site Identity:
100
100
93.3
60
N.A.
33.3
N.A.
N.A.
N.A.
6.6
N.A.
13.3
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
100
100
80
N.A.
53.3
N.A.
N.A.
N.A.
20
N.A.
26.6
N.A.
N.A.
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
0
0
0
0
0
0
0
13
38
0
0
0
0
13
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
25
0
0
0
% D
% Glu:
0
13
13
0
0
13
0
0
0
0
0
50
63
13
13
% E
% Phe:
0
0
0
0
0
0
13
0
0
0
0
0
0
0
0
% F
% Gly:
0
50
0
13
0
0
0
13
0
13
0
0
0
0
0
% G
% His:
0
13
0
0
13
0
0
13
0
0
0
0
0
0
0
% H
% Ile:
13
0
0
13
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
63
0
0
13
0
0
0
13
50
13
13
0
0
% L
% Met:
38
13
0
0
0
13
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
25
0
0
63
25
0
0
13
0
0
0
25
13
% N
% Pro:
0
0
0
0
0
0
0
13
13
0
13
0
13
0
0
% P
% Gln:
13
0
0
0
0
0
0
0
0
13
0
0
0
0
0
% Q
% Arg:
13
0
0
50
63
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
13
13
0
50
13
13
0
25
0
0
0
50
% S
% Thr:
0
0
0
13
13
0
13
50
13
0
0
0
0
63
13
% T
% Val:
13
13
0
0
0
0
0
0
0
0
13
13
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
50
13
0
0
13
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _