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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WAPAL
All Species:
9.7
Human Site:
Y452
Identified Species:
23.7
UniProt:
Q7Z5K2
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z5K2
NP_055860.1
1190
132946
Y452
S
S
N
Y
K
I
K
Y
F
G
F
D
D
L
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_864834
1208
134719
Y458
S
S
N
Y
K
I
K
Y
F
G
F
D
D
L
S
Cat
Felis silvestris
Mouse
Mus musculus
Q65Z40
1200
134037
Y461
S
S
N
Y
K
I
K
Y
F
G
F
D
D
L
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516111
530
59846
Chicken
Gallus gallus
XP_421493
1199
133498
F462
S
N
Y
K
I
K
Y
F
G
F
D
D
L
S
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_688605
1142
126031
K421
S
A
A
R
E
R
K
K
N
K
K
A
E
A
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W517
1741
185137
R756
K
R
N
T
R
G
T
R
G
S
R
K
A
E
Q
Honey Bee
Apis mellifera
XP_395593
1191
132953
D452
P
E
P
E
T
E
P
D
P
E
P
E
P
D
T
Nematode Worm
Caenorhab. elegans
NP_500567
746
84072
T90
E
M
L
S
Q
S
S
T
S
S
L
N
R
R
M
Sea Urchin
Strong. purpuratus
XP_780081
513
57225
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
94.5
N.A.
92.7
N.A.
N.A.
42.2
80.9
N.A.
60
N.A.
22.8
25.2
21.2
20.1
Protein Similarity:
100
N.A.
N.A.
96.4
N.A.
95.5
N.A.
N.A.
43.6
87.9
N.A.
73.7
N.A.
37
44.1
37.4
30.5
P-Site Identity:
100
N.A.
N.A.
100
N.A.
100
N.A.
N.A.
0
13.3
N.A.
13.3
N.A.
6.6
0
0
0
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
N.A.
N.A.
0
26.6
N.A.
33.3
N.A.
13.3
13.3
13.3
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
0
0
0
0
0
0
0
0
10
10
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
10
0
0
10
40
30
10
0
% D
% Glu:
10
10
0
10
10
10
0
0
0
10
0
10
10
10
20
% E
% Phe:
0
0
0
0
0
0
0
10
30
10
30
0
0
0
0
% F
% Gly:
0
0
0
0
0
10
0
0
20
30
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
10
30
0
0
0
0
0
0
0
0
0
% I
% Lys:
10
0
0
10
30
10
40
10
0
10
10
10
0
0
0
% K
% Leu:
0
0
10
0
0
0
0
0
0
0
10
0
10
30
0
% L
% Met:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
10
40
0
0
0
0
0
10
0
0
10
0
0
0
% N
% Pro:
10
0
10
0
0
0
10
0
10
0
10
0
10
0
0
% P
% Gln:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
10
% Q
% Arg:
0
10
0
10
10
10
0
10
0
0
10
0
10
10
0
% R
% Ser:
50
30
0
10
0
10
10
0
10
20
0
0
0
10
30
% S
% Thr:
0
0
0
10
10
0
10
10
0
0
0
0
0
0
10
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
30
0
0
10
30
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _