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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ARHGAP22
All Species:
13.03
Human Site:
S437
Identified Species:
40.95
UniProt:
Q7Z5H3
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z5H3
NP_067049.2
698
76779
S437
S
S
F
R
Q
P
R
S
L
S
G
S
P
K
G
Chimpanzee
Pan troglodytes
XP_001137732
698
76536
S437
S
S
F
R
Q
P
R
S
L
S
G
S
P
K
G
Rhesus Macaque
Macaca mulatta
XP_001108619
697
76710
S437
S
S
F
R
Q
P
G
S
R
S
G
S
P
K
G
Dog
Lupus familis
XP_849790
666
74702
V400
H
S
V
Q
N
G
T
V
R
M
G
I
L
N
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8BL80
702
77767
S444
S
S
F
R
Q
Q
G
S
R
S
E
S
P
K
G
Rat
Rattus norvegicus
Q5U2Z7
748
84125
V482
H
S
V
Q
N
G
T
V
R
M
G
I
L
N
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_421651
734
81722
R473
P
P
W
K
Y
S
F
R
Q
Q
G
A
R
S
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_690970
695
77458
S436
K
Q
V
K
S
L
P
S
W
K
Y
S
F
K
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.9
97.2
45.1
N.A.
82.4
47.1
N.A.
N.A.
66
N.A.
59.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.5
97.7
59.1
N.A.
87.6
60.9
N.A.
N.A.
75.1
N.A.
72.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
86.6
13.3
N.A.
73.3
13.3
N.A.
N.A.
13.3
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
86.6
20
N.A.
73.3
20
N.A.
N.A.
33.3
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
13
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
13
0
0
0
0
% E
% Phe:
0
0
50
0
0
0
13
0
0
0
0
0
13
0
0
% F
% Gly:
0
0
0
0
0
25
25
0
0
0
75
0
0
0
63
% G
% His:
25
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
25
0
0
0
% I
% Lys:
13
0
0
25
0
0
0
0
0
13
0
0
0
63
0
% K
% Leu:
0
0
0
0
0
13
0
0
25
0
0
0
25
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
25
0
0
0
0
0
% M
% Asn:
0
0
0
0
25
0
0
0
0
0
0
0
0
25
0
% N
% Pro:
13
13
0
0
0
38
13
0
0
0
0
0
50
0
13
% P
% Gln:
0
13
0
25
50
13
0
0
13
13
0
0
0
0
0
% Q
% Arg:
0
0
0
50
0
0
25
13
50
0
0
0
13
0
0
% R
% Ser:
50
75
0
0
13
13
0
63
0
50
0
63
0
13
13
% S
% Thr:
0
0
0
0
0
0
25
0
0
0
0
0
0
0
13
% T
% Val:
0
0
38
0
0
0
0
25
0
0
0
0
0
0
0
% V
% Trp:
0
0
13
0
0
0
0
0
13
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
13
0
0
0
0
0
13
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _