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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIF21A
All Species:
2.73
Human Site:
S1274
Identified Species:
5.45
UniProt:
Q7Z4S6
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z4S6
NP_060111.2
1674
187179
S1274
E
A
S
L
S
P
P
S
S
P
P
S
R
P
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001099469
1663
184637
S1261
S
P
L
T
R
R
K
S
Y
D
R
G
Q
S
I
Dog
Lupus familis
XP_547366
1470
163982
E1089
G
L
Q
V
A
Q
K
E
A
Q
I
R
L
L
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9QXL2
1672
186518
L1272
S
G
A
S
E
T
S
L
S
P
P
S
S
P
P
Rat
Rattus norvegicus
Q7M6Z5
1394
158861
K1013
E
N
S
P
T
E
E
K
V
K
I
S
E
Q
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521746
1544
171654
S1142
S
P
L
T
R
R
K
S
Y
D
R
G
Q
P
I
Chicken
Gallus gallus
Q90640
1225
138905
K844
Q
I
A
D
L
Q
Q
K
L
L
D
A
D
N
G
Frog
Xenopus laevis
Q91784
1226
138905
A845
L
Q
Q
K
L
L
D
A
D
G
E
E
E
M
V
Zebra Danio
Brachydanio rerio
Q58G59
1363
154819
L982
S
Q
A
L
S
Q
D
L
L
T
L
S
S
R
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_394542
1442
161348
S1061
L
S
R
R
D
S
T
S
P
R
P
L
R
R
P
Nematode Worm
Caenorhab. elegans
P46873
699
78760
L318
Y
D
E
T
L
S
T
L
R
Y
A
N
R
A
K
Sea Urchin
Strong. purpuratus
P46871
742
84184
I361
L
R
E
F
Q
E
E
I
S
R
L
K
Q
A
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
56.5
50
N.A.
93.7
24.9
N.A.
55.2
26.8
28.2
23.4
N.A.
N.A.
43.9
22.3
22.2
Protein Similarity:
100
N.A.
72.5
64.6
N.A.
96.4
43.9
N.A.
70.8
44.6
43.4
43.1
N.A.
N.A.
60.1
30.5
32.5
P-Site Identity:
100
N.A.
6.6
0
N.A.
33.3
20
N.A.
13.3
0
0
20
N.A.
N.A.
20
6.6
6.6
P-Site Similarity:
100
N.A.
13.3
20
N.A.
40
26.6
N.A.
20
20
6.6
26.6
N.A.
N.A.
26.6
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
25
0
9
0
0
9
9
0
9
9
0
17
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
9
9
0
17
0
9
17
9
0
9
0
0
% D
% Glu:
17
0
17
0
9
17
17
9
0
0
9
9
17
0
9
% E
% Phe:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
9
0
0
0
0
0
0
0
9
0
17
0
0
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
9
0
0
0
0
0
9
0
0
17
0
0
0
25
% I
% Lys:
0
0
0
9
0
0
25
17
0
9
0
9
0
0
9
% K
% Leu:
25
9
17
17
25
9
0
25
17
9
17
9
9
9
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% M
% Asn:
0
9
0
0
0
0
0
0
0
0
0
9
0
9
0
% N
% Pro:
0
17
0
9
0
9
9
0
9
17
25
0
0
25
17
% P
% Gln:
9
17
17
0
9
25
9
0
0
9
0
0
25
9
0
% Q
% Arg:
0
9
9
9
17
17
0
0
9
17
17
9
25
17
9
% R
% Ser:
34
9
17
9
17
17
9
34
25
0
0
34
17
9
0
% S
% Thr:
0
0
0
25
9
9
17
0
0
9
0
0
0
0
0
% T
% Val:
0
0
0
9
0
0
0
0
9
0
0
0
0
0
17
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
0
0
17
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _