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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GDF7
All Species:
16.36
Human Site:
S197
Identified Species:
32.73
UniProt:
Q7Z4P5
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z4P5
NP_878248.2
450
46950
S197
R
A
P
R
L
L
Y
S
R
A
A
E
P
L
V
Chimpanzee
Pan troglodytes
XP_001164592
501
55399
V280
Q
P
A
A
L
L
D
V
R
S
V
P
G
L
D
Rhesus Macaque
Macaca mulatta
XP_001096970
447
47002
S194
R
A
P
R
L
L
Y
S
R
A
A
E
P
L
V
Dog
Lupus familis
XP_542974
499
55131
V278
Q
P
A
A
L
L
D
V
R
S
V
P
G
L
D
Cat
Felis silvestris
Mouse
Mus musculus
P43029
461
47872
S190
G
T
A
H
L
L
H
S
R
A
A
E
P
L
G
Rat
Rattus norvegicus
Q6HA10
452
50994
S200
L
S
P
L
L
L
D
S
R
T
L
D
P
Q
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511410
181
19862
Chicken
Gallus gallus
Q90751
353
40328
L148
S
K
D
P
V
T
R
L
L
D
T
R
L
V
H
Frog
Xenopus laevis
P25703
398
45557
S186
V
K
P
A
A
A
A
S
R
G
P
V
V
R
L
Zebra Danio
Brachydanio rerio
P85857
404
46271
S184
R
S
I
D
L
Q
D
S
R
K
A
E
W
E
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P07713
588
65849
S229
T
L
V
E
I
E
K
S
L
L
S
L
F
N
M
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P48969
461
51863
S238
R
S
P
V
Y
L
D
S
T
I
V
G
A
G
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
31.1
95.1
30.8
N.A.
81.1
45.1
N.A.
29.7
26
28.8
42.4
N.A.
25
N.A.
N.A.
20.6
Protein Similarity:
100
43.7
96.2
42.8
N.A.
84.8
55.9
N.A.
34
39.3
42.4
56.6
N.A.
39.1
N.A.
N.A.
33.8
P-Site Identity:
100
26.6
100
26.6
N.A.
60
40
N.A.
0
0
20
46.6
N.A.
6.6
N.A.
N.A.
26.6
P-Site Similarity:
100
40
100
40
N.A.
66.6
53.3
N.A.
0
13.3
26.6
53.3
N.A.
26.6
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
17
25
25
9
9
9
0
0
25
34
0
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
9
0
0
42
0
0
9
0
9
0
0
25
% D
% Glu:
0
0
0
9
0
9
0
0
0
0
0
34
0
9
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% F
% Gly:
9
0
0
0
0
0
0
0
0
9
0
9
17
9
17
% G
% His:
0
0
0
9
0
0
9
0
0
0
0
0
0
0
9
% H
% Ile:
0
0
9
0
9
0
0
0
0
9
0
0
0
0
0
% I
% Lys:
0
17
0
0
0
0
9
0
0
9
0
0
0
0
0
% K
% Leu:
9
9
0
9
59
59
0
9
17
9
9
9
9
42
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% N
% Pro:
0
17
42
9
0
0
0
0
0
0
9
17
34
0
0
% P
% Gln:
17
0
0
0
0
9
0
0
0
0
0
0
0
9
0
% Q
% Arg:
34
0
0
17
0
0
9
0
67
0
0
9
0
9
0
% R
% Ser:
9
25
0
0
0
0
0
67
0
17
9
0
0
0
0
% S
% Thr:
9
9
0
0
0
9
0
0
9
9
9
0
0
0
0
% T
% Val:
9
0
9
9
9
0
0
17
0
0
25
9
9
9
25
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% W
% Tyr:
0
0
0
0
9
0
17
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _