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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GDF7
All Species:
9.39
Human Site:
S133
Identified Species:
18.79
UniProt:
Q7Z4P5
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z4P5
NP_878248.2
450
46950
S133
D
Q
A
T
Q
D
E
S
A
A
E
T
G
Q
S
Chimpanzee
Pan troglodytes
XP_001164592
501
55399
G214
D
K
G
Q
D
D
R
G
P
V
V
R
K
Q
R
Rhesus Macaque
Macaca mulatta
XP_001096970
447
47002
S130
D
Q
A
T
Q
D
E
S
A
A
E
T
G
Q
S
Dog
Lupus familis
XP_542974
499
55131
G212
D
K
G
Q
D
D
R
G
P
V
V
R
K
Q
R
Cat
Felis silvestris
Mouse
Mus musculus
P43029
461
47872
E129
Q
D
E
T
A
A
A
E
P
G
Q
S
F
L
F
Rat
Rattus norvegicus
Q6HA10
452
50994
S140
D
R
G
L
D
D
L
S
H
T
P
L
R
R
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511410
181
19862
Chicken
Gallus gallus
Q90751
353
40328
F88
S
G
K
T
A
R
R
F
F
F
N
L
T
S
I
Frog
Xenopus laevis
P25703
398
45557
S126
S
M
E
E
I
P
E
S
R
E
K
T
I
Q
R
Zebra Danio
Brachydanio rerio
P85857
404
46271
T116
D
K
G
K
D
D
L
T
L
S
P
L
R
R
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P07713
588
65849
A159
H
Q
P
K
Q
A
S
A
S
T
E
S
H
Q
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P48969
461
51863
V155
F
N
Y
T
R
N
E
V
Q
A
V
S
Q
A
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
31.1
95.1
30.8
N.A.
81.1
45.1
N.A.
29.7
26
28.8
42.4
N.A.
25
N.A.
N.A.
20.6
Protein Similarity:
100
43.7
96.2
42.8
N.A.
84.8
55.9
N.A.
34
39.3
42.4
56.6
N.A.
39.1
N.A.
N.A.
33.8
P-Site Identity:
100
20
100
20
N.A.
6.6
20
N.A.
0
6.6
26.6
13.3
N.A.
33.3
N.A.
N.A.
20
P-Site Similarity:
100
26.6
100
26.6
N.A.
20
33.3
N.A.
0
6.6
33.3
40
N.A.
53.3
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
17
0
17
17
9
9
17
25
0
0
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
50
9
0
0
34
50
0
0
0
0
0
0
0
0
9
% D
% Glu:
0
0
17
9
0
0
34
9
0
9
25
0
0
0
0
% E
% Phe:
9
0
0
0
0
0
0
9
9
9
0
0
9
0
9
% F
% Gly:
0
9
34
0
0
0
0
17
0
9
0
0
17
0
0
% G
% His:
9
0
0
0
0
0
0
0
9
0
0
0
9
0
0
% H
% Ile:
0
0
0
0
9
0
0
0
0
0
0
0
9
0
9
% I
% Lys:
0
25
9
17
0
0
0
0
0
0
9
0
17
0
0
% K
% Leu:
0
0
0
9
0
0
17
0
9
0
0
25
0
9
0
% L
% Met:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
0
0
0
9
0
0
0
0
9
0
0
0
0
% N
% Pro:
0
0
9
0
0
9
0
0
25
0
17
0
0
0
0
% P
% Gln:
9
25
0
17
25
0
0
0
9
0
9
0
9
50
17
% Q
% Arg:
0
9
0
0
9
9
25
0
9
0
0
17
17
17
25
% R
% Ser:
17
0
0
0
0
0
9
34
9
9
0
25
0
9
25
% S
% Thr:
0
0
0
42
0
0
0
9
0
17
0
25
9
0
0
% T
% Val:
0
0
0
0
0
0
0
9
0
17
25
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _