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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC46A3
All Species:
20.3
Human Site:
S253
Identified Species:
49.63
UniProt:
Q7Z3Q1
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z3Q1
NP_001129391.1
461
51519
S253
Y
M
L
F
K
N
A
S
G
K
R
R
F
L
L
Chimpanzee
Pan troglodytes
XP_001137737
461
51387
S253
Y
M
L
F
K
N
A
S
G
K
R
R
F
L
L
Rhesus Macaque
Macaca mulatta
XP_001098307
461
51583
S253
Y
M
L
F
K
N
A
S
S
K
R
R
F
L
L
Dog
Lupus familis
XP_534517
461
51305
S253
Y
M
L
F
K
N
A
S
G
R
Q
R
Y
F
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9DC26
460
51365
S253
Y
M
L
F
K
N
G
S
S
K
R
Q
A
L
L
Rat
Rattus norvegicus
Q5BK75
461
51508
S253
Y
M
L
F
K
N
G
S
C
K
R
R
S
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519811
382
41918
L175
I
R
I
A
I
V
D
L
I
L
G
L
V
T
G
Chicken
Gallus gallus
Q5F4B8
464
51380
P255
Y
M
L
F
K
T
A
P
S
K
K
R
I
L
I
Frog
Xenopus laevis
Q6DCX5
463
51182
Q253
L
F
T
H
R
H
Y
Q
S
F
F
R
L
F
T
Zebra Danio
Brachydanio rerio
Q7ZWG6
481
52169
V271
S
T
R
H
H
Q
A
V
C
R
L
Y
S
S
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
95.6
86.5
N.A.
74.8
75.4
N.A.
57
51.2
33
29.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.3
96.9
91.7
N.A.
85.6
85.9
N.A.
68.5
68.7
53.5
48.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
73.3
N.A.
73.3
80
N.A.
0
60
6.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
93.3
N.A.
80
80
N.A.
6.6
73.3
20
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
60
0
0
0
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
20
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
10
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
10
0
70
0
0
0
0
0
10
10
0
30
20
0
% F
% Gly:
0
0
0
0
0
0
20
0
30
0
10
0
0
0
10
% G
% His:
0
0
0
20
10
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
10
0
10
0
0
0
10
0
0
0
10
0
10
% I
% Lys:
0
0
0
0
70
0
0
0
0
60
10
0
0
0
0
% K
% Leu:
10
0
70
0
0
0
0
10
0
10
10
10
10
60
60
% L
% Met:
0
70
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
60
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
10
0
10
0
0
10
10
0
0
0
% Q
% Arg:
0
10
10
0
10
0
0
0
0
20
50
70
0
0
0
% R
% Ser:
10
0
0
0
0
0
0
60
40
0
0
0
20
10
0
% S
% Thr:
0
10
10
0
0
10
0
0
0
0
0
0
0
10
10
% T
% Val:
0
0
0
0
0
10
0
10
0
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
70
0
0
0
0
0
10
0
0
0
0
10
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _