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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NUP54
All Species:
22.42
Human Site:
S204
Identified Species:
41.11
UniProt:
Q7Z3B4
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z3B4
NP_059122.2
507
55435
S204
K
K
E
T
E
I
R
S
Q
Q
Q
Q
L
V
E
Chimpanzee
Pan troglodytes
XP_001150700
459
50757
V192
L
P
D
D
Q
T
E
V
V
I
Y
V
V
E
R
Rhesus Macaque
Macaca mulatta
XP_001096676
459
50756
V192
L
P
D
D
Q
T
E
V
V
I
Y
V
V
E
R
Dog
Lupus familis
XP_544935
460
48982
L193
G
D
E
R
D
A
I
L
A
K
W
N
Q
L
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8BTS4
510
55713
S207
K
K
E
T
D
I
R
S
Q
Q
Q
Q
L
V
E
Rat
Rattus norvegicus
P70582
510
55726
S207
K
K
E
T
D
I
R
S
Q
Q
Q
Q
L
V
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509878
1198
131683
S510
R
K
E
T
D
I
R
S
Q
Q
Q
Q
L
V
E
Chicken
Gallus gallus
XP_420594
503
55210
S200
R
K
E
A
D
I
R
S
Q
Q
Q
Q
L
V
E
Frog
Xenopus laevis
NP_001083202
502
55374
G199
K
K
E
S
D
I
R
G
Q
Q
Q
Q
L
V
E
Zebra Danio
Brachydanio rerio
XP_002665869
526
55848
N223
D
S
I
L
A
R
W
N
Q
L
Q
A
F
W
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V6B9
610
64378
P311
R
E
L
S
A
V
K
P
H
Q
Q
Q
V
I
Q
Honey Bee
Apis mellifera
XP_394448
621
67296
E321
K
K
K
K
D
V
K
E
G
E
V
Q
L
I
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786754
536
58274
S240
K
K
D
T
E
I
R
S
Q
Q
Q
Q
M
V
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.3
90.1
76.1
N.A.
95.4
95.2
N.A.
39.3
88.1
80.4
51.7
N.A.
37.5
38
N.A.
50
Protein Similarity:
100
90.3
90.3
78.1
N.A.
97.8
98
N.A.
40.6
93.2
89.9
64
N.A.
51.6
54.5
N.A.
65.8
P-Site Identity:
100
0
0
6.6
N.A.
93.3
93.3
N.A.
86.6
80
80
13.3
N.A.
20
26.6
N.A.
80
P-Site Similarity:
100
20
20
33.3
N.A.
100
100
N.A.
100
93.3
93.3
20
N.A.
73.3
66.6
N.A.
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
16
8
0
0
8
0
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
24
16
54
0
0
0
0
0
0
0
0
0
8
% D
% Glu:
0
8
54
0
16
0
16
8
0
8
0
0
0
16
47
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
8
0
0
0
0
0
0
8
8
0
0
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
54
8
0
0
16
0
0
0
16
0
% I
% Lys:
47
62
8
8
0
0
16
0
0
8
0
0
0
0
0
% K
% Leu:
16
0
8
8
0
0
0
8
0
8
0
0
54
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
0
8
0
0
0
% N
% Pro:
0
16
0
0
0
0
0
8
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
16
0
0
0
62
62
70
70
8
0
16
% Q
% Arg:
24
0
0
8
0
8
54
0
0
0
0
0
0
0
16
% R
% Ser:
0
8
0
16
0
0
0
47
0
0
0
0
0
0
8
% S
% Thr:
0
0
0
39
0
16
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
16
0
16
16
0
8
16
24
54
0
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
8
0
0
8
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
16
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _