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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DET1
All Species:
30.91
Human Site:
S217
Identified Species:
61.82
UniProt:
Q7L5Y6
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7L5Y6
NP_001137546.1
550
63848
S217
K
C
D
K
V
V
L
S
H
N
Q
G
L
Y
L
Chimpanzee
Pan troglodytes
XP_001164700
516
59763
V200
N
I
L
A
I
L
S
V
Q
Q
Q
T
I
H
V
Rhesus Macaque
Macaca mulatta
XP_001089083
561
65069
S228
K
C
D
K
V
V
L
S
H
N
Q
G
L
Y
L
Dog
Lupus familis
XP_536186
811
91626
S478
K
C
D
K
V
V
L
S
H
N
Q
G
L
Y
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9D0A0
550
63819
S217
K
C
D
K
V
V
L
S
H
N
Q
G
L
Y
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_413870
551
63959
S217
K
C
D
K
V
I
L
S
H
N
Q
G
L
Y
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_955964
563
65339
S229
K
C
D
K
I
I
L
S
H
N
Q
G
L
Y
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623769
555
64215
S227
K
V
D
K
I
Y
L
S
H
N
Q
G
L
Y
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795871
570
66247
S235
K
C
D
K
I
F
L
S
H
N
Q
G
L
Y
L
Poplar Tree
Populus trichocarpa
XP_002319992
530
61269
I206
V
S
L
R
Y
Q
T
I
Y
I
L
Q
I
R
E
Maize
Zea mays
NP_001147932
509
59167
G193
I
N
L
A
H
S
I
G
A
Y
M
Y
E
D
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P48732
543
62473
R217
R
I
H
L
L
Q
I
R
D
S
G
H
L
V
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.7
97.8
67.3
N.A.
99.6
N.A.
N.A.
N.A.
96.3
N.A.
86.8
N.A.
N.A.
62.1
N.A.
70.8
Protein Similarity:
100
91.4
98
67.6
N.A.
100
N.A.
N.A.
N.A.
98.7
N.A.
92.3
N.A.
N.A.
76
N.A.
79.8
P-Site Identity:
100
6.6
100
100
N.A.
100
N.A.
N.A.
N.A.
93.3
N.A.
86.6
N.A.
N.A.
80
N.A.
86.6
P-Site Similarity:
100
40
100
100
N.A.
100
N.A.
N.A.
N.A.
100
N.A.
100
N.A.
N.A.
86.6
N.A.
93.3
Percent
Protein Identity:
33.2
30
N.A.
31.6
N.A.
N.A.
Protein Similarity:
53.8
51.6
N.A.
52.3
N.A.
N.A.
P-Site Identity:
0
6.6
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
20
13.3
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
17
0
0
0
0
9
0
0
0
0
0
0
% A
% Cys:
0
59
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
67
0
0
0
0
0
9
0
0
0
0
9
9
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
9
% E
% Phe:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
9
0
0
9
67
0
0
0
% G
% His:
0
0
9
0
9
0
0
0
67
0
0
9
0
9
0
% H
% Ile:
9
17
0
0
34
17
17
9
0
9
0
0
17
0
0
% I
% Lys:
67
0
0
67
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
25
9
9
9
67
0
0
0
9
0
75
0
75
% L
% Met:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% M
% Asn:
9
9
0
0
0
0
0
0
0
67
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
17
0
0
9
9
75
9
0
0
0
% Q
% Arg:
9
0
0
9
0
0
0
9
0
0
0
0
0
9
0
% R
% Ser:
0
9
0
0
0
9
9
67
0
9
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
9
0
0
0
0
9
0
0
0
% T
% Val:
9
9
0
0
42
34
0
9
0
0
0
0
0
9
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
9
0
0
9
9
0
9
0
67
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _