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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DET1
All Species:
18.18
Human Site:
S177
Identified Species:
36.36
UniProt:
Q7L5Y6
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7L5Y6
NP_001137546.1
550
63848
S177
F
F
E
V
Y
R
N
S
E
S
V
T
P
N
P
Chimpanzee
Pan troglodytes
XP_001164700
516
59763
H160
P
L
E
D
Y
S
L
H
I
I
D
L
H
T
G
Rhesus Macaque
Macaca mulatta
XP_001089083
561
65069
S188
F
F
E
V
Y
R
N
S
E
S
V
T
P
N
P
Dog
Lupus familis
XP_536186
811
91626
S438
F
Y
E
V
Y
R
N
S
E
S
V
T
P
N
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9D0A0
550
63819
S177
F
Y
E
V
Y
R
N
S
E
S
V
T
P
N
P
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_413870
551
63959
S177
F
F
E
V
Y
R
N
S
E
S
V
T
P
N
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_955964
563
65339
N189
F
F
E
V
Y
R
N
N
E
S
V
T
P
N
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623769
555
64215
N187
F
Y
Q
I
Y
S
N
N
E
A
L
T
P
N
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795871
570
66247
N195
F
Y
D
M
Y
R
N
N
E
S
V
S
P
T
H
Poplar Tree
Populus trichocarpa
XP_002319992
530
61269
E166
T
F
H
L
L
R
L
E
D
G
V
I
L
D
E
Maize
Zea mays
NP_001147932
509
59167
A153
E
S
T
A
T
E
G
A
I
H
G
V
P
L
I
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P48732
543
62473
D177
L
D
D
G
V
V
L
D
E
R
V
F
L
H
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.7
97.8
67.3
N.A.
99.6
N.A.
N.A.
N.A.
96.3
N.A.
86.8
N.A.
N.A.
62.1
N.A.
70.8
Protein Similarity:
100
91.4
98
67.6
N.A.
100
N.A.
N.A.
N.A.
98.7
N.A.
92.3
N.A.
N.A.
76
N.A.
79.8
P-Site Identity:
100
13.3
100
93.3
N.A.
93.3
N.A.
N.A.
N.A.
100
N.A.
93.3
N.A.
N.A.
53.3
N.A.
53.3
P-Site Similarity:
100
13.3
100
100
N.A.
100
N.A.
N.A.
N.A.
100
N.A.
100
N.A.
N.A.
93.3
N.A.
86.6
Percent
Protein Identity:
33.2
30
N.A.
31.6
N.A.
N.A.
Protein Similarity:
53.8
51.6
N.A.
52.3
N.A.
N.A.
P-Site Identity:
20
6.6
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
40
13.3
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
0
0
9
0
9
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
17
9
0
0
0
9
9
0
9
0
0
9
9
% D
% Glu:
9
0
59
0
0
9
0
9
75
0
0
0
0
0
9
% E
% Phe:
67
42
0
0
0
0
0
0
0
0
0
9
0
0
0
% F
% Gly:
0
0
0
9
0
0
9
0
0
9
9
0
0
0
9
% G
% His:
0
0
9
0
0
0
0
9
0
9
0
0
9
9
9
% H
% Ile:
0
0
0
9
0
0
0
0
17
9
0
9
0
0
9
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
9
9
0
9
9
0
25
0
0
0
9
9
17
9
0
% L
% Met:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
67
25
0
0
0
0
0
59
0
% N
% Pro:
9
0
0
0
0
0
0
0
0
0
0
0
75
0
59
% P
% Gln:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
67
0
0
0
9
0
0
0
0
0
% R
% Ser:
0
9
0
0
0
17
0
42
0
59
0
9
0
0
0
% S
% Thr:
9
0
9
0
9
0
0
0
0
0
0
59
0
17
0
% T
% Val:
0
0
0
50
9
9
0
0
0
0
75
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
34
0
0
75
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _