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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIAA1539 All Species: 15.76
Human Site: S131 Identified Species: 38.52
UniProt: Q7L5A3 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7L5A3 NP_079458.2 538 56690 S131 C V V E Q R S S V T S S W T S
Chimpanzee Pan troglodytes XP_001165916 538 56738 S131 C V V E Q R S S V T S S W T S
Rhesus Macaque Macaca mulatta XP_001090314 538 56684 S131 C V V E Q R S S V T S S W T S
Dog Lupus familis XP_852785 536 56436 S129 C V V E Q G G S S T S P W T S
Cat Felis silvestris
Mouse Mus musculus Q8BR27 538 57056 N131 C V V E H G G N T T S P W T S
Rat Rattus norvegicus Q5PQM8 538 56972 S131 R V V E Q G G S A T S S W T S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZI58 1093 122387 V376 L L Q E R Q E V I A R I A Q H
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q1LV22 1021 113458 W219 A A D E E L I W N F S Q T P S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610688 1297 137494 N213 S S A G G G T N N S S A A S S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_799179 409 45632 D18 T K G A S R G D V P L D E G A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 98.6 93.6 N.A. 91 91.8 N.A. N.A. 25.6 N.A. 25.7 N.A. 21.1 N.A. N.A. 29.7
Protein Similarity: 100 99 98.6 95.1 N.A. 92.9 93.4 N.A. N.A. 34.7 N.A. 34.7 N.A. 27.6 N.A. N.A. 44.2
P-Site Identity: 100 100 100 73.3 N.A. 60 73.3 N.A. N.A. 6.6 N.A. 20 N.A. 13.3 N.A. N.A. 13.3
P-Site Similarity: 100 100 100 73.3 N.A. 66.6 73.3 N.A. N.A. 33.3 N.A. 26.6 N.A. 46.6 N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 10 10 10 0 0 0 0 10 10 0 10 20 0 10 % A
% Cys: 50 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 10 0 0 0 0 10 0 0 0 10 0 0 0 % D
% Glu: 0 0 0 80 10 0 10 0 0 0 0 0 10 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % F
% Gly: 0 0 10 10 10 40 40 0 0 0 0 0 0 10 0 % G
% His: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 10 % H
% Ile: 0 0 0 0 0 0 10 0 10 0 0 10 0 0 0 % I
% Lys: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 10 10 0 0 0 10 0 0 0 0 10 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 20 20 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 10 0 20 0 10 0 % P
% Gln: 0 0 10 0 50 10 0 0 0 0 0 10 0 10 0 % Q
% Arg: 10 0 0 0 10 40 0 0 0 0 10 0 0 0 0 % R
% Ser: 10 10 0 0 10 0 30 50 10 10 80 40 0 10 80 % S
% Thr: 10 0 0 0 0 0 10 0 10 60 0 0 10 60 0 % T
% Val: 0 60 60 0 0 0 0 10 40 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 10 0 0 0 0 60 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _