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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCM10
All Species:
26.67
Human Site:
Y725
Identified Species:
48.89
UniProt:
Q7L590
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7L590
NP_060988.3
875
98183
Y725
K
R
R
E
Q
L
A
Y
L
E
S
E
E
F
Q
Chimpanzee
Pan troglodytes
XP_001140870
874
98112
Y724
K
R
R
E
Q
L
A
Y
L
E
S
E
E
F
Q
Rhesus Macaque
Macaca mulatta
XP_001085751
873
97875
Y724
K
R
R
E
Q
L
A
Y
L
E
S
E
E
F
Q
Dog
Lupus familis
XP_544256
875
97644
Y725
K
R
R
E
Q
L
T
Y
L
E
S
E
E
F
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q0VBD2
885
98387
Y735
K
R
R
E
Q
L
A
Y
L
E
S
E
E
F
Q
Rat
Rattus norvegicus
NP_001100836
889
98964
Y739
K
R
R
E
Q
L
A
Y
L
E
S
E
E
F
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_423055
729
81488
K594
K
I
L
N
A
K
S
K
H
M
S
V
L
K
E
Frog
Xenopus laevis
Q5EAW4
860
95399
Y710
K
H
R
D
Q
L
A
Y
L
E
S
E
E
F
Q
Zebra Danio
Brachydanio rerio
Q5RHY1
833
92421
I692
Q
S
E
E
F
Q
R
I
L
N
A
K
S
S
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VIE6
776
86505
A641
V
E
M
R
E
R
E
A
Q
E
E
Y
F
N
K
Honey Bee
Apis mellifera
XP_001121461
641
73638
D506
K
S
Y
E
E
E
K
D
K
Y
F
N
K
L
E
Nematode Worm
Caenorhab. elegans
NP_499456
691
76034
K556
I
R
A
M
L
A
R
K
S
T
H
H
K
E
A
Sea Urchin
Strong. purpuratus
XP_782384
703
78261
N568
D
E
M
D
K
I
L
N
A
K
S
S
H
A
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
94.6
83.1
N.A.
74.6
76.8
N.A.
N.A.
53.5
58
45.9
N.A.
28.6
27.2
25
29.3
Protein Similarity:
100
99.5
97.4
90.7
N.A.
84.7
86.1
N.A.
N.A.
66.1
72.8
62.9
N.A.
47.4
44.4
42.6
45.2
P-Site Identity:
100
100
100
93.3
N.A.
100
100
N.A.
N.A.
13.3
86.6
13.3
N.A.
6.6
13.3
6.6
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
N.A.
26.6
93.3
33.3
N.A.
20
33.3
13.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
8
8
47
8
8
0
8
0
0
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
16
0
0
0
8
0
0
0
0
0
0
0
% D
% Glu:
0
16
8
62
16
8
8
0
0
62
8
54
54
8
16
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
8
0
8
54
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% G
% His:
0
8
0
0
0
0
0
0
8
0
8
8
8
0
0
% H
% Ile:
8
8
0
0
0
8
0
8
0
0
0
0
0
0
0
% I
% Lys:
70
0
0
0
8
8
8
16
8
8
0
8
16
8
8
% K
% Leu:
0
0
8
0
8
54
8
0
62
0
0
0
8
8
0
% L
% Met:
0
0
16
8
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
0
8
0
8
0
8
0
8
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
0
0
0
54
8
0
0
8
0
0
0
0
0
54
% Q
% Arg:
0
54
54
8
0
8
16
0
0
0
0
0
0
0
0
% R
% Ser:
0
16
0
0
0
0
8
0
8
0
70
8
8
8
0
% S
% Thr:
0
0
0
0
0
0
8
0
0
8
0
0
0
0
0
% T
% Val:
8
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
54
0
8
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _