KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCM10
All Species:
22.12
Human Site:
Y460
Identified Species:
40.56
UniProt:
Q7L590
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7L590
NP_060988.3
875
98183
Y460
R
L
C
Q
D
G
F
Y
Y
G
G
V
S
S
A
Chimpanzee
Pan troglodytes
XP_001140870
874
98112
Y459
R
L
C
Q
D
G
F
Y
Y
G
G
V
S
S
A
Rhesus Macaque
Macaca mulatta
XP_001085751
873
97875
Y459
R
L
C
Q
D
G
F
Y
Y
G
G
V
S
S
A
Dog
Lupus familis
XP_544256
875
97644
Y460
R
L
C
Q
D
G
F
Y
Y
G
G
V
S
S
A
Cat
Felis silvestris
Mouse
Mus musculus
Q0VBD2
885
98387
Y475
R
L
C
Q
D
G
F
Y
Y
G
G
V
S
S
E
Rat
Rattus norvegicus
NP_001100836
889
98964
Y479
R
L
C
Q
D
G
F
Y
Y
G
G
V
S
S
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_423055
729
81488
A344
S
N
M
V
V
R
G
A
D
A
I
V
Q
E
T
Frog
Xenopus laevis
Q5EAW4
860
95399
H450
R
L
C
Q
G
G
F
H
Y
G
G
V
S
S
M
Zebra Danio
Brachydanio rerio
Q5RHY1
833
92421
P440
M
S
S
L
A
C
A
P
S
M
S
A
P
Q
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VIE6
776
86505
E391
N
K
V
L
G
K
N
E
V
F
Y
G
G
Q
T
Honey Bee
Apis mellifera
XP_001121461
641
73638
K256
S
K
D
M
G
K
C
K
S
K
K
K
N
G
E
Nematode Worm
Caenorhab. elegans
NP_499456
691
76034
V306
K
L
S
A
K
R
G
V
F
N
A
V
T
C
G
Sea Urchin
Strong. purpuratus
XP_782384
703
78261
D318
S
F
K
S
S
K
L
D
L
K
S
L
G
V
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
94.6
83.1
N.A.
74.6
76.8
N.A.
N.A.
53.5
58
45.9
N.A.
28.6
27.2
25
29.3
Protein Similarity:
100
99.5
97.4
90.7
N.A.
84.7
86.1
N.A.
N.A.
66.1
72.8
62.9
N.A.
47.4
44.4
42.6
45.2
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
N.A.
6.6
80
0
N.A.
0
0
13.3
0
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
N.A.
6.6
86.6
0
N.A.
0
6.6
33.3
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
8
0
8
8
0
8
8
8
0
0
31
% A
% Cys:
0
0
54
0
0
8
8
0
0
0
0
0
0
8
0
% C
% Asp:
0
0
8
0
47
0
0
8
8
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
8
0
0
0
0
0
8
24
% E
% Phe:
0
8
0
0
0
0
54
0
8
8
0
0
0
0
0
% F
% Gly:
0
0
0
0
24
54
16
0
0
54
54
8
16
8
8
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% I
% Lys:
8
16
8
0
8
24
0
8
0
16
8
8
0
0
8
% K
% Leu:
0
62
0
16
0
0
8
0
8
0
0
8
0
0
0
% L
% Met:
8
0
8
8
0
0
0
0
0
8
0
0
0
0
8
% M
% Asn:
8
8
0
0
0
0
8
0
0
8
0
0
8
0
0
% N
% Pro:
0
0
0
0
0
0
0
8
0
0
0
0
8
0
8
% P
% Gln:
0
0
0
54
0
0
0
0
0
0
0
0
8
16
0
% Q
% Arg:
54
0
0
0
0
16
0
0
0
0
0
0
0
0
0
% R
% Ser:
24
8
16
8
8
0
0
0
16
0
16
0
54
54
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
16
% T
% Val:
0
0
8
8
8
0
0
8
8
0
0
70
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
47
54
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _