KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCM10
All Species:
21.21
Human Site:
T527
Identified Species:
38.89
UniProt:
Q7L590
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7L590
NP_060988.3
875
98183
T527
K
E
L
M
D
L
P
T
C
G
A
R
N
L
K
Chimpanzee
Pan troglodytes
XP_001140870
874
98112
T526
K
E
L
M
D
L
P
T
C
G
A
R
N
L
K
Rhesus Macaque
Macaca mulatta
XP_001085751
873
97875
T526
K
E
L
M
D
L
P
T
C
G
A
R
N
L
K
Dog
Lupus familis
XP_544256
875
97644
T527
K
E
L
M
D
L
P
T
F
G
A
R
N
L
K
Cat
Felis silvestris
Mouse
Mus musculus
Q0VBD2
885
98387
T542
R
E
L
M
A
L
P
T
F
G
A
R
N
L
Q
Rat
Rattus norvegicus
NP_001100836
889
98964
T546
R
E
L
M
A
L
P
T
F
G
A
R
N
L
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_423055
729
81488
L411
S
I
S
A
S
A
L
L
K
Q
Q
K
Q
K
L
Frog
Xenopus laevis
Q5EAW4
860
95399
P517
E
L
M
T
L
P
T
P
G
A
L
N
L
K
K
Zebra Danio
Brachydanio rerio
Q5RHY1
833
92421
G507
S
K
S
S
A
V
A
G
S
S
V
Q
S
V
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VIE6
776
86505
R458
E
R
G
G
P
V
S
R
L
A
G
G
V
E
A
Honey Bee
Apis mellifera
XP_001121461
641
73638
M323
Q
K
P
S
L
N
H
M
P
E
F
H
T
V
V
Nematode Worm
Caenorhab. elegans
NP_499456
691
76034
K373
T
P
T
S
G
L
K
K
I
T
K
E
E
E
K
Sea Urchin
Strong. purpuratus
XP_782384
703
78261
K385
R
H
M
V
K
V
E
K
T
K
K
N
V
S
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
94.6
83.1
N.A.
74.6
76.8
N.A.
N.A.
53.5
58
45.9
N.A.
28.6
27.2
25
29.3
Protein Similarity:
100
99.5
97.4
90.7
N.A.
84.7
86.1
N.A.
N.A.
66.1
72.8
62.9
N.A.
47.4
44.4
42.6
45.2
P-Site Identity:
100
100
100
93.3
N.A.
73.3
73.3
N.A.
N.A.
0
6.6
0
N.A.
0
0
13.3
0
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
N.A.
6.6
20
33.3
N.A.
13.3
20
13.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
24
8
8
0
0
16
47
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
24
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
31
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
16
47
0
0
0
0
8
0
0
8
0
8
8
16
0
% E
% Phe:
0
0
0
0
0
0
0
0
24
0
8
0
0
0
0
% F
% Gly:
0
0
8
8
8
0
0
8
8
47
8
8
0
0
0
% G
% His:
0
8
0
0
0
0
8
0
0
0
0
8
0
0
0
% H
% Ile:
0
8
0
0
0
0
0
0
8
0
0
0
0
0
0
% I
% Lys:
31
16
0
0
8
0
8
16
8
8
16
8
0
16
47
% K
% Leu:
0
8
47
0
16
54
8
8
8
0
8
0
8
47
8
% L
% Met:
0
0
16
47
0
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
0
0
0
0
16
47
0
0
% N
% Pro:
0
8
8
0
8
8
47
8
8
0
0
0
0
0
0
% P
% Gln:
8
0
0
0
0
0
0
0
0
8
8
8
8
0
16
% Q
% Arg:
24
8
0
0
0
0
0
8
0
0
0
47
0
0
0
% R
% Ser:
16
0
16
24
8
0
8
0
8
8
0
0
8
8
8
% S
% Thr:
8
0
8
8
0
0
8
47
8
8
0
0
8
0
8
% T
% Val:
0
0
0
8
0
24
0
0
0
0
8
0
16
16
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _