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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCM10
All Species:
25.45
Human Site:
T305
Identified Species:
46.67
UniProt:
Q7L590
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7L590
NP_060988.3
875
98183
T305
G
V
I
L
K
K
V
T
P
Q
S
V
N
S
G
Chimpanzee
Pan troglodytes
XP_001140870
874
98112
T304
G
V
I
L
K
K
V
T
P
Q
S
V
N
S
G
Rhesus Macaque
Macaca mulatta
XP_001085751
873
97875
T304
G
V
I
L
K
K
V
T
P
Q
S
G
N
N
G
Dog
Lupus familis
XP_544256
875
97644
T305
G
V
I
L
K
K
I
T
P
Q
S
C
N
S
G
Cat
Felis silvestris
Mouse
Mus musculus
Q0VBD2
885
98387
T321
G
V
I
L
R
K
V
T
P
Q
S
A
T
S
G
Rat
Rattus norvegicus
NP_001100836
889
98964
T325
G
V
I
L
R
K
V
T
P
Q
S
A
N
S
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_423055
729
81488
L193
S
F
N
L
I
S
Y
L
L
V
V
N
E
K
L
Frog
Xenopus laevis
Q5EAW4
860
95399
T296
G
V
I
V
K
K
I
T
P
Q
S
S
N
N
G
Zebra Danio
Brachydanio rerio
Q5RHY1
833
92421
I288
N
N
G
K
T
F
S
I
W
K
L
N
D
L
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VIE6
776
86505
L240
D
W
V
I
A
G
A
L
V
S
K
N
P
V
K
Honey Bee
Apis mellifera
XP_001121461
641
73638
K105
D
I
K
S
L
L
K
K
V
I
S
K
D
I
Y
Nematode Worm
Caenorhab. elegans
NP_499456
691
76034
K155
L
E
K
L
S
N
L
K
P
T
S
N
F
K
E
Sea Urchin
Strong. purpuratus
XP_782384
703
78261
A167
R
K
I
M
R
T
D
A
K
G
K
A
F
S
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
94.6
83.1
N.A.
74.6
76.8
N.A.
N.A.
53.5
58
45.9
N.A.
28.6
27.2
25
29.3
Protein Similarity:
100
99.5
97.4
90.7
N.A.
84.7
86.1
N.A.
N.A.
66.1
72.8
62.9
N.A.
47.4
44.4
42.6
45.2
P-Site Identity:
100
100
86.6
86.6
N.A.
80
86.6
N.A.
N.A.
6.6
73.3
0
N.A.
0
6.6
20
13.3
P-Site Similarity:
100
100
93.3
93.3
N.A.
86.6
93.3
N.A.
N.A.
6.6
93.3
13.3
N.A.
13.3
20
26.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
8
8
0
0
0
24
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
16
0
0
0
0
0
8
0
0
0
0
0
16
0
0
% D
% Glu:
0
8
0
0
0
0
0
0
0
0
0
0
8
0
8
% E
% Phe:
0
8
0
0
0
8
0
0
0
0
0
0
16
0
0
% F
% Gly:
54
0
8
0
0
8
0
0
0
8
0
8
0
0
54
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
8
62
8
8
0
16
8
0
8
0
0
0
8
8
% I
% Lys:
0
8
16
8
39
54
8
16
8
8
16
8
0
16
8
% K
% Leu:
8
0
0
62
8
8
8
16
8
0
8
0
0
8
8
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
8
8
0
0
8
0
0
0
0
0
31
47
16
0
% N
% Pro:
0
0
0
0
0
0
0
0
62
0
0
0
8
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
54
0
0
0
0
0
% Q
% Arg:
8
0
0
0
24
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
8
0
0
8
8
8
8
0
0
8
70
8
0
47
0
% S
% Thr:
0
0
0
0
8
8
0
54
0
8
0
0
8
0
0
% T
% Val:
0
54
8
8
0
0
39
0
16
8
8
16
0
8
0
% V
% Trp:
0
8
0
0
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _