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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCM10
All Species:
15.15
Human Site:
T217
Identified Species:
27.78
UniProt:
Q7L590
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7L590
NP_060988.3
875
98183
T217
A
P
S
Q
P
L
Q
T
I
S
R
N
K
P
S
Chimpanzee
Pan troglodytes
XP_001140870
874
98112
T216
A
P
S
Q
P
L
Q
T
I
S
R
N
K
P
S
Rhesus Macaque
Macaca mulatta
XP_001085751
873
97875
T216
A
P
S
Q
P
L
Q
T
I
S
Q
N
K
P
S
Dog
Lupus familis
XP_544256
875
97644
T216
T
S
P
Q
P
L
R
T
T
P
G
N
K
P
S
Cat
Felis silvestris
Mouse
Mus musculus
Q0VBD2
885
98387
G233
P
S
P
Q
A
V
P
G
N
K
C
S
R
T
I
Rat
Rattus norvegicus
NP_001100836
889
98964
G237
P
S
P
Q
A
V
P
G
N
K
C
S
G
M
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_423055
729
81488
T108
L
Q
P
V
S
V
E
T
F
S
G
L
R
L
R
Frog
Xenopus laevis
Q5EAW4
860
95399
P208
M
A
S
F
L
S
P
P
E
K
S
S
A
R
P
Zebra Danio
Brachydanio rerio
Q5RHY1
833
92421
T202
P
L
I
K
T
P
P
T
V
R
Q
P
T
P
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VIE6
776
86505
R155
N
P
H
N
P
I
K
R
Q
S
A
V
S
T
T
Honey Bee
Apis mellifera
XP_001121461
641
73638
I20
D
S
D
S
D
I
D
I
L
N
D
L
L
A
N
Nematode Worm
Caenorhab. elegans
NP_499456
691
76034
L70
L
Y
V
K
K
R
E
L
T
E
Q
G
A
L
L
Sea Urchin
Strong. purpuratus
XP_782384
703
78261
S82
G
S
V
G
D
R
G
S
Q
K
S
M
P
H
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
94.6
83.1
N.A.
74.6
76.8
N.A.
N.A.
53.5
58
45.9
N.A.
28.6
27.2
25
29.3
Protein Similarity:
100
99.5
97.4
90.7
N.A.
84.7
86.1
N.A.
N.A.
66.1
72.8
62.9
N.A.
47.4
44.4
42.6
45.2
P-Site Identity:
100
100
93.3
53.3
N.A.
6.6
6.6
N.A.
N.A.
13.3
6.6
13.3
N.A.
20
0
0
0
P-Site Similarity:
100
100
100
60
N.A.
26.6
26.6
N.A.
N.A.
33.3
13.3
33.3
N.A.
40
26.6
20
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
24
8
0
0
16
0
0
0
0
0
8
0
16
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
16
0
0
0
0
% C
% Asp:
8
0
8
0
16
0
8
0
0
0
8
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
16
0
8
8
0
0
0
0
0
% E
% Phe:
0
0
0
8
0
0
0
0
8
0
0
0
0
0
0
% F
% Gly:
8
0
0
8
0
0
8
16
0
0
16
8
8
0
0
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
0
8
0
0
16
0
8
24
0
0
0
0
0
8
% I
% Lys:
0
0
0
16
8
0
8
0
0
31
0
0
31
0
0
% K
% Leu:
16
8
0
0
8
31
0
8
8
0
0
16
8
16
16
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
8
0
8
0
% M
% Asn:
8
0
0
8
0
0
0
0
16
8
0
31
0
0
8
% N
% Pro:
24
31
31
0
39
8
31
8
0
8
0
8
8
39
8
% P
% Gln:
0
8
0
47
0
0
24
0
16
0
24
0
0
0
0
% Q
% Arg:
0
0
0
0
0
16
8
8
0
8
16
0
16
8
16
% R
% Ser:
0
39
31
8
8
8
0
8
0
39
16
24
8
0
31
% S
% Thr:
8
0
0
0
8
0
0
47
16
0
0
0
8
16
16
% T
% Val:
0
0
16
8
0
24
0
0
8
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _