KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCM10
All Species:
12.73
Human Site:
S706
Identified Species:
23.33
UniProt:
Q7L590
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7L590
NP_060988.3
875
98183
S706
E
K
N
T
M
F
S
S
Q
A
E
D
E
L
E
Chimpanzee
Pan troglodytes
XP_001140870
874
98112
S705
E
K
N
T
M
F
S
S
Q
A
E
D
E
L
E
Rhesus Macaque
Macaca mulatta
XP_001085751
873
97875
S705
E
K
N
T
M
F
S
S
Q
A
E
D
E
L
E
Dog
Lupus familis
XP_544256
875
97644
P706
E
K
N
H
N
F
S
P
E
A
E
D
E
L
E
Cat
Felis silvestris
Mouse
Mus musculus
Q0VBD2
885
98387
P718
E
N
S
N
T
V
S
P
E
E
E
L
E
P
A
Rat
Rattus norvegicus
NP_001100836
889
98964
P722
E
N
S
N
T
V
S
P
E
D
E
L
E
P
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_423055
729
81488
Y579
K
R
R
E
Q
V
A
Y
L
E
S
E
E
F
Q
Frog
Xenopus laevis
Q5EAW4
860
95399
P691
A
S
H
A
S
T
S
P
K
S
P
D
E
N
E
Zebra Danio
Brachydanio rerio
Q5RHY1
833
92421
R677
E
E
P
A
M
K
K
R
R
E
Q
L
E
Y
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VIE6
776
86505
A626
R
I
E
K
I
M
A
A
T
S
S
H
T
N
L
Honey Bee
Apis mellifera
XP_001121461
641
73638
S491
K
E
M
M
Q
T
K
S
T
H
T
D
L
I
E
Nematode Worm
Caenorhab. elegans
NP_499456
691
76034
P541
P
E
P
E
A
K
K
P
R
S
Q
K
M
D
E
Sea Urchin
Strong. purpuratus
XP_782384
703
78261
G553
K
K
R
K
T
F
L
G
Q
D
V
K
M
S
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
94.6
83.1
N.A.
74.6
76.8
N.A.
N.A.
53.5
58
45.9
N.A.
28.6
27.2
25
29.3
Protein Similarity:
100
99.5
97.4
90.7
N.A.
84.7
86.1
N.A.
N.A.
66.1
72.8
62.9
N.A.
47.4
44.4
42.6
45.2
P-Site Identity:
100
100
100
73.3
N.A.
26.6
26.6
N.A.
N.A.
6.6
26.6
20
N.A.
0
20
6.6
20
P-Site Similarity:
100
100
100
80
N.A.
40
40
N.A.
N.A.
40
46.6
40
N.A.
26.6
40
33.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
16
8
0
16
8
0
31
0
0
0
0
16
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
16
0
47
0
8
0
% D
% Glu:
54
24
8
16
0
0
0
0
24
24
47
8
70
0
54
% E
% Phe:
0
0
0
0
0
39
0
0
0
0
0
0
0
8
0
% F
% Gly:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% G
% His:
0
0
8
8
0
0
0
0
0
8
0
8
0
0
0
% H
% Ile:
0
8
0
0
8
0
0
0
0
0
0
0
0
8
8
% I
% Lys:
24
39
0
16
0
16
24
0
8
0
0
16
0
0
8
% K
% Leu:
0
0
0
0
0
0
8
0
8
0
0
24
8
31
8
% L
% Met:
0
0
8
8
31
8
0
0
0
0
0
0
16
0
0
% M
% Asn:
0
16
31
16
8
0
0
0
0
0
0
0
0
16
0
% N
% Pro:
8
0
16
0
0
0
0
39
0
0
8
0
0
16
0
% P
% Gln:
0
0
0
0
16
0
0
0
31
0
16
0
0
0
8
% Q
% Arg:
8
8
16
0
0
0
0
8
16
0
0
0
0
0
0
% R
% Ser:
0
8
16
0
8
0
54
31
0
24
16
0
0
8
0
% S
% Thr:
0
0
0
24
24
16
0
0
16
0
8
0
8
0
0
% T
% Val:
0
0
0
0
0
24
0
0
0
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _