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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCM10
All Species:
21.52
Human Site:
S600
Identified Species:
39.44
UniProt:
Q7L590
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7L590
NP_060988.3
875
98183
S600
S
P
A
V
P
S
S
S
R
Q
P
P
A
Q
P
Chimpanzee
Pan troglodytes
XP_001140870
874
98112
S599
S
P
A
V
P
S
S
S
R
Q
P
P
A
Q
P
Rhesus Macaque
Macaca mulatta
XP_001085751
873
97875
S599
S
P
A
V
P
S
S
S
R
Q
P
P
A
Q
P
Dog
Lupus familis
XP_544256
875
97644
S600
S
P
A
V
T
P
S
S
Q
R
V
P
S
Q
S
Cat
Felis silvestris
Mouse
Mus musculus
Q0VBD2
885
98387
S612
S
P
A
V
P
S
S
S
R
Q
A
A
A
Q
S
Rat
Rattus norvegicus
NP_001100836
889
98964
S616
S
A
A
V
P
S
S
S
R
Q
P
A
A
Q
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_423055
729
81488
F481
R
P
R
L
G
T
G
F
S
E
G
E
D
I
L
Frog
Xenopus laevis
Q5EAW4
860
95399
T587
S
E
K
S
S
T
L
T
S
S
A
C
S
V
F
Zebra Danio
Brachydanio rerio
Q5RHY1
833
92421
S579
E
G
P
K
G
S
G
S
S
L
S
G
P
A
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VIE6
776
86505
G528
P
D
K
F
K
N
R
G
F
S
F
D
A
S
L
Honey Bee
Apis mellifera
XP_001121461
641
73638
N393
N
N
N
I
E
K
K
N
L
N
M
L
S
S
N
Nematode Worm
Caenorhab. elegans
NP_499456
691
76034
D443
F
G
E
F
L
A
A
D
T
R
R
E
K
A
A
Sea Urchin
Strong. purpuratus
XP_782384
703
78261
D455
R
G
W
S
E
E
G
D
I
D
L
G
A
S
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
94.6
83.1
N.A.
74.6
76.8
N.A.
N.A.
53.5
58
45.9
N.A.
28.6
27.2
25
29.3
Protein Similarity:
100
99.5
97.4
90.7
N.A.
84.7
86.1
N.A.
N.A.
66.1
72.8
62.9
N.A.
47.4
44.4
42.6
45.2
P-Site Identity:
100
100
100
53.3
N.A.
80
80
N.A.
N.A.
6.6
6.6
13.3
N.A.
6.6
0
0
13.3
P-Site Similarity:
100
100
100
73.3
N.A.
80
80
N.A.
N.A.
26.6
26.6
13.3
N.A.
13.3
26.6
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
47
0
0
8
8
0
0
0
16
16
54
16
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
8
0
0
0
0
0
16
0
8
0
8
8
0
0
% D
% Glu:
8
8
8
0
16
8
0
0
0
8
0
16
0
0
0
% E
% Phe:
8
0
0
16
0
0
0
8
8
0
8
0
0
0
8
% F
% Gly:
0
24
0
0
16
0
24
8
0
0
8
16
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
0
0
8
0
0
0
0
8
0
% I
% Lys:
0
0
16
8
8
8
8
0
0
0
0
0
8
0
0
% K
% Leu:
0
0
0
8
8
0
8
0
8
8
8
8
0
0
16
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
8
8
8
0
0
8
0
8
0
8
0
0
0
0
8
% N
% Pro:
8
47
8
0
39
8
0
0
0
0
31
31
8
0
31
% P
% Gln:
0
0
0
0
0
0
0
0
8
39
0
0
0
47
0
% Q
% Arg:
16
0
8
0
0
0
8
0
39
16
8
0
0
0
0
% R
% Ser:
54
0
0
16
8
47
47
54
24
16
8
0
24
24
24
% S
% Thr:
0
0
0
0
8
16
0
8
8
0
0
0
0
0
0
% T
% Val:
0
0
0
47
0
0
0
0
0
0
8
0
0
8
8
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _