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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCM10
All Species:
22.73
Human Site:
S577
Identified Species:
41.67
UniProt:
Q7L590
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7L590
NP_060988.3
875
98183
S577
L
E
M
R
R
R
K
S
E
E
I
Q
K
R
F
Chimpanzee
Pan troglodytes
XP_001140870
874
98112
S576
L
E
M
R
R
R
K
S
E
E
I
Q
K
R
F
Rhesus Macaque
Macaca mulatta
XP_001085751
873
97875
S576
L
E
M
R
R
R
K
S
E
E
I
Q
K
R
F
Dog
Lupus familis
XP_544256
875
97644
S577
L
E
M
R
K
K
R
S
E
E
I
Q
K
R
F
Cat
Felis silvestris
Mouse
Mus musculus
Q0VBD2
885
98387
S589
L
E
M
R
K
R
R
S
E
D
I
Q
K
R
F
Rat
Rattus norvegicus
NP_001100836
889
98964
S593
L
E
M
R
K
R
K
S
E
E
I
Q
K
R
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_423055
729
81488
K458
Q
P
S
L
P
S
P
K
P
G
A
E
F
P
K
Frog
Xenopus laevis
Q5EAW4
860
95399
K564
Q
M
L
N
A
R
K
K
R
A
E
E
S
Q
K
Zebra Danio
Brachydanio rerio
Q5RHY1
833
92421
R556
G
A
P
V
A
S
S
R
P
N
V
S
R
G
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VIE6
776
86505
E505
L
G
S
D
N
K
K
E
S
E
A
G
T
P
A
Honey Bee
Apis mellifera
XP_001121461
641
73638
G370
E
Q
I
N
K
S
R
G
W
K
V
A
L
L
S
Nematode Worm
Caenorhab. elegans
NP_499456
691
76034
F420
S
V
E
E
M
I
E
F
L
G
T
T
G
G
E
Sea Urchin
Strong. purpuratus
XP_782384
703
78261
R432
S
T
L
T
E
S
T
R
F
N
A
A
T
P
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
94.6
83.1
N.A.
74.6
76.8
N.A.
N.A.
53.5
58
45.9
N.A.
28.6
27.2
25
29.3
Protein Similarity:
100
99.5
97.4
90.7
N.A.
84.7
86.1
N.A.
N.A.
66.1
72.8
62.9
N.A.
47.4
44.4
42.6
45.2
P-Site Identity:
100
100
100
80
N.A.
80
93.3
N.A.
N.A.
0
13.3
0
N.A.
20
0
0
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
6.6
33.3
13.3
N.A.
26.6
40
6.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
16
0
0
0
0
8
24
16
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
0
0
0
8
0
0
0
0
0
% D
% Glu:
8
47
8
8
8
0
8
8
47
47
8
16
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
8
8
0
0
0
8
0
47
% F
% Gly:
8
8
0
0
0
0
0
8
0
16
0
8
8
16
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
8
0
0
0
0
47
0
0
0
0
% I
% Lys:
0
0
0
0
31
16
47
16
0
8
0
0
47
0
16
% K
% Leu:
54
0
16
8
0
0
0
0
8
0
0
0
8
8
0
% L
% Met:
0
8
47
0
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
16
8
0
0
0
0
16
0
0
0
0
0
% N
% Pro:
0
8
8
0
8
0
8
0
16
0
0
0
0
24
16
% P
% Gln:
16
8
0
0
0
0
0
0
0
0
0
47
0
8
0
% Q
% Arg:
0
0
0
47
24
47
24
16
8
0
0
0
8
47
0
% R
% Ser:
16
0
16
0
0
31
8
47
8
0
0
8
8
0
8
% S
% Thr:
0
8
0
8
0
0
8
0
0
0
8
8
16
0
0
% T
% Val:
0
8
0
8
0
0
0
0
0
0
16
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _