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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCM10
All Species:
13.03
Human Site:
S543
Identified Species:
23.89
UniProt:
Q7L590
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7L590
NP_060988.3
875
98183
S543
H
L
A
K
A
T
A
S
G
I
M
G
S
P
K
Chimpanzee
Pan troglodytes
XP_001140870
874
98112
S542
H
L
A
K
A
T
A
S
G
I
M
G
S
P
K
Rhesus Macaque
Macaca mulatta
XP_001085751
873
97875
S542
H
L
A
K
T
T
T
S
G
I
M
G
I
P
K
Dog
Lupus familis
XP_544256
875
97644
P543
H
L
A
K
A
R
L
P
G
I
T
G
S
P
K
Cat
Felis silvestris
Mouse
Mus musculus
Q0VBD2
885
98387
S558
H
L
A
R
A
K
A
S
G
S
S
K
P
A
I
Rat
Rattus norvegicus
NP_001100836
889
98964
S562
H
L
A
R
A
K
S
S
G
S
P
K
P
A
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_423055
729
81488
E427
E
A
R
K
K
R
S
E
E
I
Q
R
R
F
L
Frog
Xenopus laevis
Q5EAW4
860
95399
A533
L
S
G
V
S
P
Q
A
N
C
G
K
E
G
Q
Zebra Danio
Brachydanio rerio
Q5RHY1
833
92421
K523
S
D
L
L
K
Q
Q
K
E
Q
H
Q
Q
R
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VIE6
776
86505
L474
R
K
Q
R
V
Q
D
L
E
R
L
R
L
L
K
Honey Bee
Apis mellifera
XP_001121461
641
73638
E339
M
K
S
K
K
L
E
E
K
D
A
K
R
D
E
Nematode Worm
Caenorhab. elegans
NP_499456
691
76034
Q389
S
L
N
D
L
L
S
Q
R
K
N
T
F
A
A
Sea Urchin
Strong. purpuratus
XP_782384
703
78261
Q401
S
A
D
N
L
L
K
Q
H
K
Q
E
M
A
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
94.6
83.1
N.A.
74.6
76.8
N.A.
N.A.
53.5
58
45.9
N.A.
28.6
27.2
25
29.3
Protein Similarity:
100
99.5
97.4
90.7
N.A.
84.7
86.1
N.A.
N.A.
66.1
72.8
62.9
N.A.
47.4
44.4
42.6
45.2
P-Site Identity:
100
100
80
73.3
N.A.
46.6
40
N.A.
N.A.
13.3
0
0
N.A.
6.6
6.6
6.6
0
P-Site Similarity:
100
100
80
73.3
N.A.
53.3
53.3
N.A.
N.A.
20
20
0
N.A.
20
20
13.3
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
47
0
39
0
24
8
0
0
8
0
0
31
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
0
8
8
8
0
0
8
0
0
8
0
0
0
8
0
% D
% Glu:
8
0
0
0
0
0
8
16
24
0
0
8
8
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
8
8
0
% F
% Gly:
0
0
8
0
0
0
0
0
47
0
8
31
0
8
0
% G
% His:
47
0
0
0
0
0
0
0
8
0
8
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
39
0
0
8
0
16
% I
% Lys:
0
16
0
47
24
16
8
8
8
16
0
31
0
0
39
% K
% Leu:
8
54
8
8
16
24
8
8
0
0
8
0
8
8
8
% L
% Met:
8
0
0
0
0
0
0
0
0
0
24
0
8
0
8
% M
% Asn:
0
0
8
8
0
0
0
0
8
0
8
0
0
0
0
% N
% Pro:
0
0
0
0
0
8
0
8
0
0
8
0
16
31
0
% P
% Gln:
0
0
8
0
0
16
16
16
0
8
16
8
8
0
8
% Q
% Arg:
8
0
8
24
0
16
0
0
8
8
0
16
16
8
0
% R
% Ser:
24
8
8
0
8
0
24
39
0
16
8
0
24
0
8
% S
% Thr:
0
0
0
0
8
24
8
0
0
0
8
8
0
0
0
% T
% Val:
0
0
0
8
8
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _