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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MCM10 All Species: 11.21
Human Site: S150 Identified Species: 20.56
UniProt: Q7L590 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7L590 NP_060988.3 875 98183 S150 S P A R L Q K S P V E K S P R
Chimpanzee Pan troglodytes XP_001140870 874 98112 S150 S P A R L Q K S P E K S P R P
Rhesus Macaque Macaca mulatta XP_001085751 873 97875 S150 S P A R L Q K S P E K S P R P
Dog Lupus familis XP_544256 875 97644 S150 S S P L P P K S V D K S S R P
Cat Felis silvestris
Mouse Mus musculus Q0VBD2 885 98387 P147 G T A P L Q E P P D S S L Q P
Rat Rattus norvegicus NP_001100836 889 98964 P151 S S A P L H E P P G A S L R P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_423055 729 81488 P42 A Q L D N P L P T A K R G N Q
Frog Xenopus laevis Q5EAW4 860 95399 S139 S P G N P K K S P E N K M V Q
Zebra Danio Brachydanio rerio Q5RHY1 833 92421 P134 A G V K T T P P T V R D S D G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VIE6 776 86505 S88 K E P E L D S S D D E E V K N
Honey Bee Apis mellifera XP_001121461 641 73638
Nematode Worm Caenorhab. elegans NP_499456 691 76034
Sea Urchin Strong. purpuratus XP_782384 703 78261 E16 K V S R Y S C E V C A K S F T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.8 94.6 83.1 N.A. 74.6 76.8 N.A. N.A. 53.5 58 45.9 N.A. 28.6 27.2 25 29.3
Protein Similarity: 100 99.5 97.4 90.7 N.A. 84.7 86.1 N.A. N.A. 66.1 72.8 62.9 N.A. 47.4 44.4 42.6 45.2
P-Site Identity: 100 60 60 26.6 N.A. 26.6 26.6 N.A. N.A. 0 40 13.3 N.A. 20 0 0 20
P-Site Similarity: 100 66.6 66.6 33.3 N.A. 33.3 33.3 N.A. N.A. 26.6 53.3 26.6 N.A. 26.6 0 0 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 16 0 39 0 0 0 0 0 0 8 16 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 8 0 0 8 0 0 0 0 0 % C
% Asp: 0 0 0 8 0 8 0 0 8 24 0 8 0 8 0 % D
% Glu: 0 8 0 8 0 0 16 8 0 24 16 8 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % F
% Gly: 8 8 8 0 0 0 0 0 0 8 0 0 8 0 8 % G
% His: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 16 0 0 8 0 8 39 0 0 0 31 24 0 8 0 % K
% Leu: 0 0 8 8 47 0 8 0 0 0 0 0 16 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % M
% Asn: 0 0 0 8 8 0 0 0 0 0 8 0 0 8 8 % N
% Pro: 0 31 16 16 16 16 8 31 47 0 0 0 16 8 39 % P
% Gln: 0 8 0 0 0 31 0 0 0 0 0 0 0 8 16 % Q
% Arg: 0 0 0 31 0 0 0 0 0 0 8 8 0 31 8 % R
% Ser: 47 16 8 0 0 8 8 47 0 0 8 39 31 0 0 % S
% Thr: 0 8 0 0 8 8 0 0 16 0 0 0 0 0 8 % T
% Val: 0 8 8 0 0 0 0 0 16 16 0 0 8 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _