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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM73B
All Species:
23.03
Human Site:
T218
Identified Species:
56.3
UniProt:
Q7L4E1
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7L4E1
NP_116198.2
593
65531
T218
D
G
L
R
N
P
E
T
A
S
E
P
L
S
E
Chimpanzee
Pan troglodytes
XP_001162465
593
65496
T218
D
G
L
R
N
P
E
T
A
S
E
P
L
S
E
Rhesus Macaque
Macaca mulatta
XP_001118706
679
74400
T304
D
G
L
R
N
P
E
T
A
S
E
P
L
S
E
Dog
Lupus familis
XP_548426
593
65678
T218
D
S
L
R
N
P
E
T
A
S
E
V
P
S
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8BK03
593
65529
T218
D
S
L
Q
N
P
D
T
A
S
E
A
L
S
E
Rat
Rattus norvegicus
NP_001100036
554
61374
T218
D
S
L
Q
N
P
D
T
S
S
E
A
L
S
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518111
553
61225
S209
A
S
E
D
S
F
F
S
A
T
E
L
L
D
C
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6GR21
589
65263
Q216
Q
V
N
D
L
L
N
Q
S
C
S
E
G
L
S
Zebra Danio
Brachydanio rerio
Q5BLE2
596
66238
S214
S
A
S
N
S
Q
G
S
E
L
V
E
R
H
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572476
525
59005
L193
T
L
Q
E
Q
S
E
L
L
F
L
D
Q
R
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
84
92.9
N.A.
92.5
84.6
N.A.
71.1
N.A.
70.9
62
N.A.
30
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
84.8
95.6
N.A.
96.9
89.3
N.A.
77.2
N.A.
82.1
77.1
N.A.
47.8
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
80
N.A.
73.3
66.6
N.A.
20
N.A.
0
0
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
80
N.A.
86.6
86.6
N.A.
40
N.A.
6.6
13.3
N.A.
6.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
0
0
0
0
0
60
0
0
20
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
10
% C
% Asp:
60
0
0
20
0
0
20
0
0
0
0
10
0
10
0
% D
% Glu:
0
0
10
10
0
0
50
0
10
0
70
20
0
0
60
% E
% Phe:
0
0
0
0
0
10
10
0
0
10
0
0
0
0
0
% F
% Gly:
0
30
0
0
0
0
10
0
0
0
0
0
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
10
60
0
10
10
0
10
10
10
10
10
60
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
10
60
0
10
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
60
0
0
0
0
0
30
10
0
0
% P
% Gln:
10
0
10
20
10
10
0
10
0
0
0
0
10
0
0
% Q
% Arg:
0
0
0
40
0
0
0
0
0
0
0
0
10
10
0
% R
% Ser:
10
40
10
0
20
10
0
20
20
60
10
0
0
60
30
% S
% Thr:
10
0
0
0
0
0
0
60
0
10
0
0
0
0
0
% T
% Val:
0
10
0
0
0
0
0
0
0
0
10
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _